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Type	Result	AUM ($B)

Form 13F Holdings
Firm	Period	DFND	Voting	Shares
Deerfield Management Company LP	[2025-06-30]	DFND	4,779,864	4,779,864
BlackRock, Inc.	[2025-06-30]	SOLE	3,780,685	3,887,265
8 Knots Management LLC	[2025-06-30]	SOLE	3,853,067	3,853,067
UBS Group AG	[2025-06-30]	DFND	3,342,297	3,343,725
Vanguard Group Inc	[2025-06-30]	SOLE	0	3,048,645
Arex Capital Management LP	[2025-06-30]	SOLE	2,482,556	2,482,556
Jana Partners Management LP	[2025-06-30]	SOLE	2,137,145	2,137,145
Dimensional Fund Advisors LP	[2025-06-30]	SOLE	1,873,787	1,923,801
Systematic Financial Management LP	[2025-06-30]	DFND	1,121,126	1,863,926
Paradice Investment Management LLC	[2025-06-30]	DFND	0	1,736,964
Kent Lake PR LLC	[2025-06-30]	SOLE	1,200,000	1,200,000
Geode Capital Management LLC	[2025-06-30]	DFND	1,182,993	1,182,993
State Street Corp	[2025-06-30]	DFND	1,014,198	1,082,774
Goldman Sachs Group Inc	[2025-06-30]	DFND	1,066,849	1,067,162
Iron Triangle Partners LP	[2025-06-30]	SOLE	1,027,972	1,027,972
D. E. Shaw & Co., Inc.	[2025-06-30]	DFND	995,185	995,185
Ameriprise Financial Inc	[2025-06-30]	DFND	0	861,666
Arrowstreet Capital Limited Partnership	[2025-06-30]	DFND	640,074	640,074
JPMorgan Chase & Co	[2025-06-30]	DFND	496,093	563,554
Qube Research & Technologies Ltd	[2025-06-30]	SOLE	516,828	516,828
Marshall Wace LLP	[2025-06-30]	OTR	0	497,982
Citadel Advisors LLC	[2025-06-30]	DFND	482,649	482,649
Charles Schwab Investment Management Inc	[2025-06-30]	SOLE	471,825	471,825
Morgan Stanley	[2025-06-30]	DFND	436,141	438,753
Northern Trust Corp	[2025-06-30]	DFND	430,768	431,102
DekaBank Deutsche Girozentrale	[2025-06-30]	DFND	423,412	423,412
Renaissance Technologies LLC	[2025-06-30]	SOLE	405,068	405,068
Bridgeway Capital Management LLC	[2025-06-30]	SOLE	399,359	399,359
Bank of America Corp /DE/	[2025-06-30]	DFND	22,350	396,956
Phocas Financial Corp.	[2025-06-30]	SOLE	47,165	320,957
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