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Type	Result	AUM ($B)

Form 13F Holdings
Firm	Period	DFND	Voting	Shares
Soleus Capital Management LP	[2025-06-30]	SOLE	1,323,877	1,323,877
ProSight Management LP	[2025-06-30]	SOLE	900,000	900,000
Vanguard Group Inc	[2025-06-30]	SOLE	0	766,657
Susquehanna International Group LLP	[2025-06-30]	OTR	132,695	743,095
Acorn Capital Advisors LLC	[2025-06-30]	SOLE	653,779	653,779
OrbiMed Advisors LLC	[2025-06-30]	DFND	272,500	588,800
Newtyn Management LLC	[2025-06-30]	SOLE	570,000	570,000
LMR Partners LLP	[2025-06-30]	SOLE	516,417	516,417
Diametric Capital LP	[2025-06-30]	DFND	350,000	350,000
Millennium Management LLC	[2025-06-30]	SOLE	316,040	316,040
BlackRock, Inc.	[2025-06-30]	SOLE	286,398	286,401
RBF Capital, LLC	[2025-06-30]	SOLE	283,912	283,912
Geode Capital Management LLC	[2025-06-30]	DFND	174,761	174,761
Verition Fund Management LLC	[2025-06-30]	SOLE	157,500	157,500
Citadel Advisors LLC	[2025-06-30]	DFND	153,852	153,852
Prelude Capital Management LLC	[2025-06-30]	OTR	0	136,934
PRIMECAP Management Co/CA/	[2025-06-30]	SOLE	92,800	92,800
Limestone Investment Advisors LP	[2025-06-30]	SOLE	91,364	91,364
Jane Street Group LLC	[2025-06-30]	DFND	0	89,700
HGC Investment Management Inc.	[2025-06-30]	SOLE	87,968	87,968
State Street Corp	[2025-06-30]	DFND	84,873	84,873
Emerald Mutual Fund Advisers Trust	[2025-06-30]	SOLE	77,567	77,567
F/m Investments LLC	[2025-06-30]	SOLE	77,567	77,567
Group One Trading LLC	[2025-06-30]	SOLE	67,100	67,100
Rangeley Capital LLC	[2025-06-30]	SOLE	46,513	46,513
Dimensional Fund Advisors LP	[2025-06-30]	SOLE	45,573	45,604
Quadrature Capital Ltd	[2025-06-30]	OTR	0	39,285
Northern Trust Corp	[2025-06-30]	DFND	36,530	36,712
Aberdeen Group plc	[2025-06-30]	DFND	32,342	32,342
Two Sigma Investments LP	[2025-06-30]	SOLE	30,598	30,598
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