OPKO Health Inc

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OPKO Health Inc
TickerOPK
CIK #0000944809
CUSIP68375N103
SectorLife Sciences - Surgical & Medical Instruments & Apparatus
Address4400 Biscayne Blvd Suite 900, Miami, FL 33137
Source [EDGAR]
Reg D Offering (Form D) Filed Raised Terms
OPKO Health Inc 2013-02-15 175.0 M Exemption: 506 · Minimum: $1,000 · Duration: One year or less · Finder's Fee: $4,500,000 · Revenue: $25,000,001 - $100,000,000
CIK Filing 2011 - 2026
[0000944809] 10-K
[0000944809] 10-Q
[0000944809] 3
[0000944809] 4
[0000944809] 5
[0000944809] 8-K
[0000944809] D
[0000944809] SC 13D
[0000944809] SC 13G
Form 13D/13G Filer Form 13D/13G Subject Filed % Owned
OPKO Health Inc Entera Bio Ltd [2025-04-02] 0.0
Rubric Capital Management LP OPKO Health Inc [2024-11-13] 6.98
Zerhouni Elias A OPKO Health Inc [2022-06-29] 2.9
Nabel Gary J OPKO Health Inc [2022-06-29] 2.9
OPKO Health Inc SEMA4 Holdings Corp [2022-05-09] 21.2
BlackRock Inc OPKO Health Inc [2020-02-07] 5.4
OPKO Health Inc Xenetic Biosciences Inc [2019-07-29] 7.0
OPKO Health Inc Biocardia Inc [2019-06-12] 5.2
OPKO Health Inc VBI Vaccines Inc/BC [2019-06-12] 6.84
OPKO Health Inc Neovasc Inc [2019-06-12] 5.0
OPKO Health Inc Non Invasive Monitoring Systems Inc /FL/ [2019-06-12] 0.5
OPKO Health Inc Sorrento Therapeutics Inc [2019-05-09] 0.0
OPKO Health Inc Phio Pharmaceuticals Corp [2019-05-09] 0.3
OPKO Health Inc Eloxx Pharmaceuticals Inc [2019-05-09] 3.6
OPKO Health Inc Cocrystal Pharma Inc [2019-05-09] 8.4
OPKO Health Inc Chromadex Corp [2019-05-09] 0.1
Vanguard Group Inc OPKO Health Inc [2019-02-11] 5.06
BlackRock Inc OPKO Health Inc [2019-02-08] 5.4
OPKO Health Inc Sevion Therapeutics Inc [2017-08-04] 37.9
OPKO Health Inc Cocrystal Pharma Inc [2017-05-10] 8.7
OPKO Health Inc VBI Vaccines Inc [2017-03-31] 15.0
OPKO Health Inc Neovasc Inc [2017-02-14] 6.0
OPKO Health Inc RXI Pharmaceuticals Corp [2017-01-12] 5.11
OPKO Health Inc Biocardia Inc [2017-01-03] 5.3
OPKO Health Inc Arno Therapeutics Inc [2013-10-31] 0.99
OPKO Health Inc RXI Pharmaceuticals Corp [2013-03-22] 20.9
Form 3/4/5 Filer 2011 - 2026
Yu Alice Lin-Tsing
OPKO Health Inc
Lachman Prem A
Medel Roger MD
Paganelli John A
Pfenniger Richard C Jr
Uppaluri Subbarao V
Frost Gamma Investments Trust
Frost Phillip MD ET AL
Rubin Steven D
Hsiao Jane Ph D
Zerhouni Elias A
Logal Adam
Nabel Gary J
Krasno Richard M
GeneDx Holdings Corp
Borisy Alexis
Lerner Richard A
Fishel Robert Scott
Cohen Jon R
Hernandez Rulfo Fernando
Japour Anthony J
Frost Nevada Investments Trust
Senesco Technologies Inc
VBI Vaccines Inc/BC
Baron Robert A
Beier Thomas E
Kolosov Dmitry
Biozone Pharmaceuticals Inc
Sorrento Therapeutics Inc
RXi Pharmaceuticals Corp
Rodriguez Juan F
Insider Transaction (Form 3/4/5) Date Action Shares Price Value ($)
Paganelli John A
Common Stock
2026-03-20 Buy 10,000 $1.14 11,400
Uppaluri Subbarao V
Stock Option (Right to Buy) · derivative
2026-03-18 Grant 50,000 $0.00
Frost Gamma Investments Trust +1
Common Stock
2025-11-21 Buy 102,371 $1.30 133,082
Frost Gamma Investments Trust +1
Common Stock
2025-11-21 Buy 3,894 $1.32 5,140
Frost Gamma Investments Trust +1
Common Stock
2025-11-21 Buy 191,490 $1.33 254,682
Frost Gamma Investments Trust +1
Common Stock
2025-11-21 Buy 192,870 $1.34 258,446
Frost Gamma Investments Trust +1
Common Stock
2025-11-21 Buy 89,375 $1.33 118,869
Frost Gamma Investments Trust +1
Common Stock
2025-11-20 Buy 24,579 $1.34 32,936
Frost Gamma Investments Trust +1
Common Stock
2025-11-20 Buy 211,948 $1.33 281,891
Frost Gamma Investments Trust +1
Common Stock
2025-11-20 Buy 47,105 $1.33 62,650
Frost Gamma Investments Trust +1
Common Stock
2025-11-20 Buy 1,757 $1.35 2,372
Frost Gamma Investments Trust +1
Common Stock
2025-11-20 Buy 161,818 $1.34 216,836
Frost Gamma Investments Trust +1
Common Stock
2025-11-20 Buy 13,664 $1.35 18,446
Frost Gamma Investments Trust +1
Common Stock
2025-11-20 Buy 119,129 $1.32 157,250
Frost Gamma Investments Trust +1
Common Stock
2025-11-19 Buy 66,504 $1.31 87,120
Frost Gamma Investments Trust +1
Common Stock
2025-11-19 Buy 30,082 $1.30 39,107
Frost Gamma Investments Trust +1
Common Stock
2025-11-19 Buy 21,236 $1.30 27,607
Frost Gamma Investments Trust +1
Common Stock
2025-11-19 Buy 12,993 $1.31 17,021
Frost Gamma Investments Trust +1
Common Stock
2025-11-19 Buy 58,160 $1.29 75,026
Frost Gamma Investments Trust +1
Common Stock
2025-11-19 Buy 155,496 $1.32 205,255
showing 20 of 200 most recent transactions
13F Ownership Over TimeHoldersShares Held
2026-03-31 236 201,387,498
2025-12-31 224 199,519,626
2025-09-30 236 198,475,551
2025-06-30 223 207,663,252
2025-03-31 257 239,884,444
2024-12-31 241 206,998,675
2024-09-30 240 203,923,160
2024-06-30 238 195,772,966
2024-03-31 231 164,721,257
2023-12-31 220 175,825,355
2023-09-30 227 168,951,953
2023-06-30 231 174,774,503
Form 13F Holdings
Firm Period DFND Voting Shares
Washington Growth Strategies LLC [2026-06-30] SOLE 0 1,356,124
Assenagon Asset Management SA [2026-06-30] SOLE 285,339 285,339
Highline Wealth Partners LLC [2026-06-30] SOLE 116,680 116,680
Zazove Associates LLC [2026-06-30] SOLE 100,000 100,000
Allied Private Wealth LLC [2026-06-30] SOLE 91,137 91,137
Wealth Enhancement Advisory Services LLC [2026-06-30] SOLE 1,210 83,994
Apella Capital LLC [2026-06-30] SOLE 0 27,021
Slatestone Wealth LLC [2026-06-30] SOLE 0 25,770
SAX Wealth Advisors LLC [2026-06-30] SOLE 0 20,050
Westmount Partners LLC [2026-06-30] SOLE 18,550 18,550
Colony Family Offices LLC [2026-06-30] SOLE 14,729 14,729
Merit Financial Group LLC [2026-06-30] OTR 0 12,351
Traphagen Investment Advisors LLC [2026-06-30] SOLE 0 11,680
Formidable Asset Management LLC [2026-06-30] SOLE 0 10,296
Diversified Trust Co [2026-06-30] SOLE 10,000 10,122
Aventura Private Wealth LLC [2026-06-30] SOLE 8,400 8,400
Farther Finance Advisors LLC [2026-06-30] SOLE 0 3,408
Merit Financial Group LLC [2026-06-30] SOLE 0 2,255
Corecap Advisors LLC [2026-06-30] SOLE 0 1,600
Gamma Investing LLC [2026-06-30] DFND 1,334 1,334
PFS Partners LLC [2026-06-30] SOLE 0 1,100
True Wealth Design LLC [2026-06-30] SOLE 0 765
Fortitude Family Office LLC [2026-06-30] SOLE 732 732
IFP Advisors LLC [2026-06-30] SOLE 387 387
Harbor Investment Advisory LLC [2026-06-30] SOLE 180 180
Salem Investment Counselors Inc [2026-06-30] SOLE 100 100
FNY Investment Advisers LLC [2026-06-30] DFND 2 2
LRI Investments LLC [2026-06-30] SOLE 1 1
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