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Type	Result	AUM ($B)

Form 13F Holdings
Firm	Period	DFND	Voting	Shares
ARK Investment Management LLC	[2025-06-30]	SOLE	13,063,586	13,892,103
Vanguard Group Inc	[2025-06-30]	SOLE	0	12,229,169
BlackRock, Inc.	[2025-06-30]	SOLE	9,101,018	9,433,030
FMR LLC	[2025-06-30]	DFND	8,963,298	8,996,404
Sumitomo Mitsui Trust Group, Inc.	[2025-06-30]	DFND	6,017,963	6,017,963
Nikko Asset Management Americas Inc	[2025-06-30]	SOLE	5,605,769	6,009,653
AQR Capital Management LLC	[2025-06-30]	DFND	3,931,166	4,000,667
Morgan Stanley	[2025-06-30]	DFND	3,310,614	3,486,955
Bank of America Corp /DE/	[2025-06-30]	DFND	29,201	3,023,489
Millennium Management LLC	[2025-06-30]	SOLE	2,883,827	2,943,827
Geode Capital Management LLC	[2025-06-30]	DFND	2,650,819	2,650,819
State Street Corp	[2025-06-30]	DFND	2,166,442	2,492,676
Jacobs Levy Equity Management Inc	[2025-06-30]	SOLE	1,870,958	2,397,739
Quantinno Capital Management LP	[2025-06-30]	SOLE	2,233,526	2,233,526
Wellington Management Group LLP	[2025-06-30]	DFND	0	1,891,273
Two Sigma Advisers LP	[2025-06-30]	SOLE	1,740,900	1,814,600
Assenagon Asset Management S.A.	[2025-06-30]	SOLE	1,711,561	1,711,561
Trexquant Investment LP	[2025-06-30]	SOLE	1,528,391	1,528,391
Voloridge Investment Management LLC	[2025-06-30]	SOLE	1,526,892	1,526,892
Renaissance Technologies LLC	[2025-06-30]	SOLE	1,472,255	1,472,255
Capital World Investors	[2025-06-30]	DFND	1,452,300	1,452,300
Blue Water Life Science Advisors LP	[2025-06-30]	SOLE	1,100,720	1,100,720
Jump Financial, LLC	[2025-06-30]	DFND	1,041,051	1,041,051
Two Sigma Investments LP	[2025-06-30]	SOLE	1,025,761	1,025,761
Northern Trust Corp	[2025-06-30]	DFND	989,978	991,385
UBS Group AG	[2025-06-30]	DFND	915,550	916,977
Charles Schwab Investment Management Inc	[2025-06-30]	SOLE	904,337	904,337
Man Group plc	[2025-06-30]	DFND	739,238	829,610
Federated Hermes Inc	[2025-06-30]	DFND	787,522	787,522
D. E. Shaw & Co., Inc.	[2025-06-30]	DFND	742,666	746,266
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