| Due Diligence for Asset Managers |
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Analyze the public filings of asset managers Dive into the EDGAR, IAPD, CAFR source data |
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| Upstream Bio Inc | |
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| Ticker | UPB |
| CIK # | 0002022626 |
| CUSIP | 91678A107 |
| Sector | Life Sciences - Pharmaceutical Preparations |
| Address | 890 Winter Street, Suite 200, Waltham, MA 02451 |
| Source | [EDGAR] |
| CIK | Filing | 2011 - 2026 |
|---|---|---|
| [0002022626] | 10-K | |
| [0002022626] | 10-Q | |
| [0002022626] | 3 | |
| [0002022626] | 4 | |
| [0002022626] | 8-K | |
| [0002022626] | SC 13D | |
| [0002022626] | SC 13G |
| Form 13D/13G Filer | Form 13D/13G Subject | Filed | % Owned |
|---|---|---|---|
| Norges Bank | Upstream Bio Inc | [2025-10-24] | 0.0 |
| Decheng Capital Global Life Sciences Fund IV LP | Upstream Bio Inc | [2025-02-14] | 0.0 |
| TCG Crossover GP I LLC | Upstream Bio Inc | [2025-02-14] | 0.0 |
| HBM Healthcare Investments Cayman Ltd | Upstream Bio Inc | [2025-02-13] | 0.0 |
| FMR LLC | Upstream Bio Inc | [2024-11-07] | 0.0 |
| AI Upstream LLC | Upstream Bio Inc | [2024-10-22] | 819410.7 |
| BCLS Fund III Investments LP | Upstream Bio Inc | [2024-10-18] | 81944.3 |
| OrbiMed Advisors LLC | Upstream Bio Inc | [2024-10-17] | 8.9 |
| Insider Transaction (Form 3/4/5) | Date | Action | Shares | Price | Value ($) |
|---|---|---|---|---|---|
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Sutherland Everett Rand
Common Stock
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2026-03-16 | Sell | 2,093 | $9.29 | 19,444 |
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Ambrose Allison
Common Stock
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2026-03-16 | Sell | 475 | $9.29 | 4,413 |
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Houghton Adam
Common Stock
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2026-03-16 | Sell | 699 | $9.29 | 6,494 |
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Gray Michael
Common Stock
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2026-03-16 | Sell | 852 | $9.29 | 7,915 |
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Deykin Aaron
Common Stock
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2026-03-16 | Sell | 894 | $9.29 | 8,305 |
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Ambrose Allison
Common Stock
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2026-01-02 | Grant | 17,000 | $0.00 | |
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Houghton Adam
Common Stock
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2026-01-02 | Grant | 25,000 | $0.00 | |
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Sutherland Everett Rand
Common Stock
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2026-01-02 | Grant | 75,000 | $0.00 | |
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Gray Michael
Stock Option (Right to Buy) · derivative
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2026-01-02 | Grant | 91,500 | $0.00 | |
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Deykin Aaron
Stock Option (Right to Buy) · derivative
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2026-01-02 | Grant | 96,000 | $0.00 | |
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Ambrose Allison
Stock Option (Right to Buy) · derivative
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2026-01-02 | Grant | 51,000 | $0.00 | |
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Houghton Adam
Stock Option (Right to Buy) · derivative
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2026-01-02 | Grant | 75,000 | $0.00 | |
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Sutherland Everett Rand
Stock Option (Right to Buy) · derivative
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2026-01-02 | Grant | 225,000 | $0.00 | |
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Gray Michael
Common Stock
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2026-01-02 | Grant | 30,500 | $0.00 | |
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Deykin Aaron
Common Stock
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2026-01-02 | Grant | 32,000 | $0.00 | |
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Beckman Daniella
Stock Option (Right to Buy) · derivative
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2025-06-10 | Grant | 17,096 | $0.00 | |
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Renaud Ronald C JR
Stock Option (Right to Buy) · derivative
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2025-06-10 | Grant | 17,096 | $0.00 | |
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Ruddy Marcella K
Stock Option (Right to Buy) · derivative
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2025-06-10 | Grant | 17,096 | $0.00 | |
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Chimovits Erez
Stock Option (Right to Buy) · derivative
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2025-06-10 | Grant | 17,096 | $0.00 | |
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Fleming Harold Edward
Stock Option (Right to Buy) · derivative
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2025-06-10 | Grant | 17,096 | $0.00 | |
| showing 20 of 56 most recent transactions | |||||
| 13F Ownership Over Time | Holders | Shares Held |
|---|---|---|
| 2026-03-31 | 143 | 45,037,814 |
| 2025-12-31 | 135 | 51,252,661 |
| 2025-09-30 | 99 | 44,916,125 |
| 2025-06-30 | 84 | 48,353,555 |
| 2025-03-31 | 80 | 43,619,158 |
| 2024-12-31 | 71 | 42,074,592 |
| Form 13F Holdings | ||||
|---|---|---|---|---|
| Firm | Period | DFND | Voting | Shares |
| Y-Intercept Hong Kong Ltd | [2026-06-30] | SOLE | 693,555 | 693,555 |
| Simplify Asset Management Inc | [2026-06-30] | SOLE | 62,113 | 62,113 |
| Wealth Enhancement Advisory Services LLC | [2026-06-30] | SOLE | 31 | 10,017 |
| Gamma Investing LLC | [2026-06-30] | DFND | 1,164 | 1,164 |
| Farther Finance Advisors LLC | [2026-06-30] | SOLE | 0 | 353 |
| IFP Advisors LLC | [2026-06-30] | SOLE | 242 | 242 |
| Physician Wealth Advisors Inc | [2026-06-30] | SOLE | 0 | 160 | Prev | Page 1 | Next |