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Type	Result	AUM ($B)

Form 13F Holdings
Firm	Period	DFND	Voting	Shares
BlackRock, Inc.	[2025-06-30]	SOLE	10,337,641	10,507,326
FMR LLC	[2025-06-30]	DFND	8,167,164	8,181,372
Politan Capital Management LP	[2025-06-30]	SOLE	4,716,536	4,716,536
Vanguard Group Inc	[2025-06-30]	SOLE	0	4,558,584
Massachusetts Financial Services Co /MA/	[2025-06-30]	SOLE	1,960,396	1,960,396
Capital Research Global Investors	[2025-06-30]	DFND	1,855,670	1,855,670
State Street Corp	[2025-06-30]	DFND	1,345,124	1,486,394
Holocene Advisors LP	[2025-06-30]	SOLE	1,243,607	1,243,607
Westfield Capital Management Co LP	[2025-06-30]	SOLE	831,732	1,181,203
Durable Capital Partners LP	[2025-06-30]	SOLE	1,163,898	1,163,898
Alyeska Investment Group LP	[2025-06-30]	SOLE	1,134,490	1,134,490
Geode Capital Management LLC	[2025-06-30]	DFND	888,249	896,418
AllianceBernstein LP	[2025-06-30]	DFND	789,149	844,067
Viking Global Investors LP	[2025-06-30]	SOLE	767,426	767,426
Morgan Stanley	[2025-06-30]	DFND	732,959	767,375
Liontrust Investment Partners LLP	[2025-06-30]	SOLE	708,300	708,300
RTW Investments LP	[2025-06-30]	SOLE	683,294	683,294
Massachusetts Financial Services Co /MA/	[2025-06-30]	DFND	0	509,997
Goldman Sachs Group Inc	[2025-06-30]	DFND	469,459	471,525
Sumitomo Mitsui Trust Group, Inc.	[2025-06-30]	DFND	471,041	471,041
Dimensional Fund Advisors LP	[2025-06-30]	SOLE	439,933	464,305
Schroder Investment Management Group	[2025-06-30]	SOLE	448,501	448,501
Ameriprise Financial Inc	[2025-06-30]	DFND	0	394,487
BAMCO Inc /NY/	[2025-06-30]	DFND	0	384,589
Charles Schwab Investment Management Inc	[2025-06-30]	SOLE	370,733	370,734
Northern Trust Corp	[2025-06-30]	DFND	364,650	366,777
Corient Private Wealth LLC	[2025-06-30]	SOLE	1,287	330,414
Bank of New York Mellon Corp	[2025-06-30]	DFND	294,667	317,238
Grantham Mayo van Otterloo & Co LLC	[2025-06-30]	SOLE	139,258	240,563
Invesco Ltd.	[2025-06-30]	DFND	0	237,303
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