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Type	Result	AUM ($B)

Form 13F Holdings
Firm	Period	DFND	Voting	Shares
Sarissa Capital Management LP	[2025-06-30]	SOLE	1,242,527	1,242,527
Kynam Capital Management LP	[2025-06-30]	SOLE	576,111	576,111
Susquehanna International Group LLP	[2025-06-30]	OTR	42,782	275,582
Eversept Partners LP	[2025-06-30]	SOLE	167,276	167,276
Morgan Stanley	[2025-06-30]	DFND	147,283	162,966
SCP Investment LP	[2025-06-30]	SOLE	125,000	125,000
Waterfront Wealth Inc	[2025-06-30]	SOLE	0	94,729
Citadel Advisors LLC	[2025-06-30]	DFND	90,356	90,356
BNP Paribas Financial Markets	[2025-06-30]	DFND	0	75,941
Two Sigma Investments LP	[2025-06-30]	SOLE	59,024	59,024
Quinn Opportunity Partners LLC	[2025-06-30]	SOLE	39,156	58,461
Raymond James Financial Inc	[2025-06-30]	DFND	0	53,594
Hayek Kallen Investment Management	[2025-06-30]	SOLE	0	51,211
Jane Street Group LLC	[2025-06-30]	DFND	49,321	49,321
Millennium Management LLC	[2025-06-30]	SOLE	45,244	45,244
LCM Capital Management Inc	[2025-06-30]	SOLE	42,911	42,911
Jump Financial, LLC	[2025-06-30]	DFND	38,430	38,430
George Kaiser Family Foundation	[2025-06-30]	OTR	0	38,197
Mercer Global Advisors Inc /ADV	[2025-06-30]	SOLE	35,000	35,027
Trexquant Investment LP	[2025-06-30]	SOLE	32,686	32,686
SEI Investments Co	[2025-06-30]	SOLE	27,913	27,913
Onedigital Investment Advisors LLC	[2025-06-30]	SOLE	0	27,611
Bleakley Financial Group LLC	[2025-06-30]	SOLE	0	23,471
State Street Corp	[2025-06-30]	DFND	20,800	21,115
Osaic Holdings Inc	[2025-06-30]	DFND	0	18,155
Two Sigma Advisers LP	[2025-06-30]	SOLE	15,140	17,370
Geode Capital Management LLC	[2025-06-30]	DFND	17,322	17,322
Bank of America Corp /DE/	[2025-06-30]	DFND	3,726	16,048
Ameriprise Financial Inc	[2025-06-30]	DFND	0	15,368
BlackRock, Inc.	[2025-06-30]	SOLE	10,213	11,068
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