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Type	Result	AUM ($B)

Form 13F Holdings
Firm	Period	DFND	Voting	Shares
BlackRock, Inc.	[2025-06-30]	SOLE	2,923,376	2,984,063
Susquehanna International Group LLP	[2025-06-30]	OTR	46,015	2,354,615
Vanguard Group Inc	[2025-06-30]	SOLE	0	2,216,456
Ikarian Capital LLC	[2025-06-30]	SOLE	2,060,200	2,060,200
State Street Corp	[2025-06-30]	DFND	1,374,968	1,466,685
Caption Management LLC	[2025-06-30]	SOLE	1,374,900	1,374,900
Geode Capital Management LLC	[2025-06-30]	DFND	963,080	963,080
LMR Partners LLP	[2025-06-30]	SOLE	752,000	752,000
Perceptive Advisors LLC	[2025-06-30]	SOLE	750,000	750,000
Boothbay Fund Management LLC	[2025-06-30]	OTR	0	746,600
Citadel Advisors LLC	[2025-06-30]	DFND	735,800	735,800
Jane Street Group LLC	[2025-06-30]	DFND	78,300	582,200
Morgan Stanley	[2025-06-30]	DFND	486,772	550,581
UBS Group AG	[2025-06-30]	DFND	548,427	549,427
Pier Capital LLC	[2025-06-30]	SOLE	238,862	367,717
Northern Trust Corp	[2025-06-30]	DFND	364,952	364,952
Black Diamond Financial LLC	[2025-06-30]	SOLE	0	277,737
Wolverine Trading LLC	[2025-06-30]	DFND	0	260,526
Woodline Partners LP	[2025-06-30]	SOLE	241,644	241,644
Balyasny Asset Management LP	[2025-06-30]	SOLE	240,000	240,000
Jump Financial, LLC	[2025-06-30]	DFND	232,536	232,536
Millennium Management LLC	[2025-06-30]	SOLE	173,848	226,348
Barclays PLC	[2025-06-30]	SOLE	225,011	225,011
JPMorgan Chase & Co	[2025-06-30]	DFND	176,997	195,189
Affinity Asset Advisors LLC	[2025-06-30]	SOLE	175,000	175,000
National Bank of Canada /FI/	[2025-06-30]	DFND	0	168,700
Oppenheimer & Co Inc	[2025-06-30]	SOLE	162,536	162,536
Two Sigma Investments LP	[2025-06-30]	SOLE	155,837	155,837
Wellington Management Group LLP	[2025-06-30]	DFND	0	131,877
HBK Sorce Advisory LLC	[2025-06-30]	SOLE	0	127,626
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