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Type	Result	AUM ($BB)

Form 13F Holdings
Firm	Period	DFND	Voting	Shares
Baillie Gifford & Co	[2023-03-31]	DFND	26,533,159.0	32,690,074.0
Vanguard Group Inc	[2023-03-31]	SOLE	0.0	26,153,142.0
BlackRock Inc.	[2023-03-31]	SOLE	22,799,112.0	25,092,579.0
OFI Invest Asset Management	[2023-03-31]	SOLE	21,434,153.0	21,434,153.0
State Street Corp	[2023-03-31]	DFND	12,172,637.0	14,076,355.0
Baillie Gifford & Co	[2023-03-31]	SOLE	11,755,775.0	13,776,097.0
Flagship Pioneering Inc	[2023-03-31]	DFND	0.0	12,886,743.0
Coatue Management LLC	[2023-03-31]	DFND	6,546,104.0	6,546,104.0
Geode Capital Management LLC	[2023-03-31]	DFND	6,227,709.0	6,244,957.0
Theleme Partners LLP	[2023-03-31]	DFND	6,112,434.0	6,112,434.0
Susquehanna International Group LLP	[2023-03-31]	DFND	280,610.0	5,124,010.0
Morgan Stanley	[2023-03-31]	DFND	3,791,574.0	4,950,573.0
Citadel Advisors LLC	[2023-03-31]	DFND	4,537,885.0	4,537,885.0
Wellington Management Group LLP	[2023-03-31]	DFND	0.0	4,292,235.0
FMR LLC	[2023-03-31]	DFND	3,665,232.0	3,964,194.0
Capital World Investors	[2023-03-31]	DFND	3,919,590.0	3,919,590.0
Goldman Sachs Group Inc	[2023-03-31]	DFND	3,102,837.0	3,225,691.0
Northern Trust Corp	[2023-03-31]	DFND	608,502.0	3,189,513.0
Banque Pictet & CIE Sa	[2023-03-31]	SOLE	0.0	3,108,835.0
Bank of New York Mellon Corp	[2023-03-31]	DFND	1,951,395.0	2,516,775.0
Legal & General Group Plc	[2023-03-31]	DFND	1,961,647.0	2,346,676.0
Invesco Ltd.	[2023-03-31]	DFND	0.0	2,316,433.0
Dimensional Fund Advisors LP	[2023-03-31]	SOLE	2,014,810.0	2,150,275.0
Manufacturers Life Insurance Company the	[2023-03-31]	DFND	2,064,807.0	2,131,973.0
JPMorgan Chase & Co	[2023-03-31]	DFND	1,561,200.0	1,882,006.0
Mawer Investment Management Ltd	[2023-03-31]	SOLE	1,843,502.0	1,865,502.0
Deutsche Bank AG	[2023-03-31]	DFND	953,124.0	1,808,427.0
Charles Schwab Investment Management Inc	[2023-03-31]	SOLE	1,792,307.0	1,792,307.0
Bank of America Corp /DE/	[2023-03-31]	DFND	70,468.0	1,697,697.0
UBS Group AG	[2023-03-31]	DFND	0.0	1,572,800.0
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