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Type	Result	AUM ($B)

Form 13F Holdings
Firm	Period	DFND	Voting	Shares
Vanguard Group Inc	[2025-06-30]	SOLE	0	4,204,873
Deerfield Management Company LP	[2025-06-30]	DFND	3,360,052	3,360,052
BlackRock, Inc.	[2025-06-30]	SOLE	3,255,566	3,306,904
TIFF Advisory Services LLC	[2025-06-30]	DFND	0	2,777,837
Balyasny Asset Management LP	[2025-06-30]	SOLE	2,518,337	2,518,337
Marshall Wace LLP	[2025-06-30]	OTR	0	1,476,946
Geode Capital Management LLC	[2025-06-30]	DFND	1,279,443	1,279,443
Wexford Capital LP	[2025-06-30]	SOLE	1,118,679	1,118,679
TIFF Advisory Services LLC	[2025-06-30]	SOLE	0	856,628
Centerbook Partners LP	[2025-06-30]	SOLE	715,899	715,899
State Street Corp	[2025-06-30]	DFND	586,136	646,257
Renaissance Technologies LLC	[2025-06-30]	SOLE	457,500	457,500
UBS Group AG	[2025-06-30]	DFND	420,373	420,373
Millennium Management LLC	[2025-06-30]	SOLE	405,009	405,009
Northern Trust Corp	[2025-06-30]	DFND	402,214	402,214
Massar Capital Management, LP	[2025-06-30]	SOLE	400,000	400,000
FourWorld Capital Management LLC	[2025-06-30]	SOLE	391,650	391,650
freeGulliver LLC	[2025-06-30]	SOLE	343,800	343,800
Josh Arnold Investment Consultant LLC	[2025-06-30]	SOLE	0	291,150
Two Sigma Investments LP	[2025-06-30]	SOLE	278,165	278,165
Manatuck Hill Partners LLC	[2025-06-30]	SOLE	249,800	249,800
Bank of New York Mellon Corp	[2025-06-30]	DFND	246,347	248,646
Portolan Capital Management LLC	[2025-06-30]	SOLE	221,512	221,512
Informed Momentum Co LLC	[2025-06-30]	SOLE	195,837	195,837
Morgan Stanley	[2025-06-30]	DFND	144,487	175,373
Goldman Sachs Group Inc	[2025-06-30]	DFND	154,632	154,632
Charles Schwab Investment Management Inc	[2025-06-30]	SOLE	147,534	147,534
Verition Fund Management LLC	[2025-06-30]	SOLE	139,763	139,763
PanAgora Asset Management Inc	[2025-06-30]	SOLE	126,985	126,985
Citizens Financial Group Inc/Ri	[2025-06-30]	DFND	0	119,000
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