Deerfield Management Company LP

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Deerfield Management Company LP
CRD #157876
SEC #801-73284
CIK #0001009258
AUM 19.08 B (2026-03-26)
Employees 189 (47% Investors, 0% Brokers)
Fees
Minimum
Phone212-551-1600
Address345 Park Avenue South
New York, NY 10010
Source [IAPD] [EDGAR] [Website] [LinkedIn]
Total AUM ($B)
2016128402010201520212027
Fees and Compensation — Form ADV Part 2A (7/31/2026) [Brochure]
ITEM 5 – FEES AND COMPENSATION

A.      Fees

          The Firm does not have a standardized fee schedule for the discretionary investment management
services it provides the Funds. The Firm receives a management fee (calculated as a percentage of , as
applicable pursuant to the relevant Fund governing documents, a Fund’s net asset value (“NAV”), the cost
basis of Fund assets, funded commitments and/or unfunded commitments). The relevant General Partner
and/or The Deerfield Partnership Foundation (“    Deerfield Foundation”), as applicable,receives performance-
based compensation (based on the realized and unrealized profits earned by a Fund or based on distributions
made by a Fund in excess of the Fund’s investors’ funded capital commitmentsor such other threshold as
set forth in the relevant Fund Memorandum). The Firm and/or the applicable General Partnerhas waived or
reduced and may waive or reduce management fees and/or performance-based compensation due with
respect to certain investors, including investors who are present or former partners or employees of the
Firm or its affiliates and their respective family members and related entities, operating partners and others
the Firm determines provide or provided value to the Firm as well as certain investors in Deerfield Private
Design Fund V, L.P . The use of fund -level borrowing, including subscription line facilities or other credit
facilities, may increase or extend the base on which management fees are calculated (for example, where
management fees are calculated with reference to invested capital, cost or other metrics that reflect a
borrowing component). The fees applicable to each Fund are disclosed in the Memorandum for such Fund.

         Management fees generally range from 50%    0. to 1.75% annually, and will generally be reduced dollar
for dollar, but not below zero on a going forward basis, by directors’ fees, consulting fees, advisory fees,
transaction fees, commitment fees, broken deal fees or other similar fees received by the Firm from
investments made by a Fund (excluding any fees or other such remuneration received by any discovery
specialist (generally employees or consultants of the Firm, 3DC or its affiliates who principally support the
discovery activities and other operations of one or more portfolio companies and research projects,
including persons who are scientific specialists, persons who may serve on a scientific advisory board, persons
who are regulatory specialists, manufacturing specialists, intellectual property speci alists, chief medical
officers, chief science officers, recruiting specialists, clinical trial specialists, scientific collaboration directors
and engineers (“Discovery Specialists ”)), operating partners (including interim operating partners),
entrepreneurs-in-residence or other similar consultants to or employees of the Firm or its affiliates). . In
addition, the following fees generally do not offset management fees: reimbursement of the Firm’s out              -of-
pocket expenses relating to a Fund or portfolio company; rent payments for access to facilities owned or
leased by theFirm or its affiliates; payments to the Firm or its affiliatesfor the use of services made available
through or at the Cure, including catering anddining services, physical security, building use and service      , data
analytics, programming, event services and space , conferences, lectures and concierge services, video
production, graphic design and communications services,and membership and residency programs;fees for
the use of or access to equipment or utilities; fees in respect of goods, facilities and intellectual property
provided by the Firm or its affiliates; fees in respect of goo ds, facilities, intellectual property and services
provided indirectly through third parties; and fees in respect ofDiscovery Specialists.

        Performance-based compensation is generallyequal to 20% of a Fund’s profits, with the exception
of Deerfield Healthcare Innovations Fund, L.P. , which is generally 25% of distributions after 300% of
contributed capital with respect to eachportfolio investment has been distributed to investorsuntil 600% of
contributed capital with respect to such portfolio investment has been distributed to investors , and
thereafter 15% of distributions with respect to such portfolio investment . In Deerfield Partners, L.P.,
performance-based compensation is subject to a “ modified high water mark” in which the performance -
based compensation is calculated at one-half the percentage otherwise applicable (that is, 10% instead of
20%) until the sum of accrued net profits for all years subsequent to the previous high water mark (excluding
any year in which there is a net loss)quals
                                      e     200% of the sum of all accrued net losses for all years subsequent
to the prior high water mark (excluding any year in which there is a net profit). In Deerfield Healthcare
Innovations Fund, L.P., the performance-based compensation is allocated to the Deerfield Foundation.
Performance-based compensation received by the Firm is charged in conformity with Rule 205      -3 under the
Investment Advisers Act of 1940, as amended (the Advisers
                                                     “       Act”).

         The governing documents of certain Funds utilizing the Private Design Strategy or Healthcare
Innovations Strategy provide that such Fund’s management fees will be calculated and charged on a basis
that generally is not tied to the Fund’s then-current net asset value.The applicable governing documentsof
certain Funds utilizing the Private Design Strategy or Healthcare Innovations Strategy provide that before
and including a certain date (the “Fee Reduction Date”), management fees generally will be charged based
on a formula tied to the amount of an investor’s capital commitment to the relevant Fund. After the Fee
...
Account Minimums and Types of Clients — Form ADV Part 2A (7/31/2026) [Brochure]
ITEM 7 – TYPES OF CLIENTS

        The Firm’s only clients are pooled investment vehicles, the Funds, and no investment advice is
provided directly to individuals or to investors in the Funds. Conditions for investing in each Fund, such as
the minimum investment amount, are stated in the respective offering documents, which note that the
General Partner of each Fund has discretion to reduce or waive the minimum investment amounts.

         Generally, investors participating in the Funds are required to meet certain suitability and net worth
qualifications, such as being (i) anaccredited
                                     “         investor” within the meaning of Rule 501 of Regulation D under
the Securities Act of 1933, as amended,and (ii) a “qualified purchaser” as defined in Section 2(a)(51) of the
Investment Company Act of 1940, as amended (“ Investment Company Act ”). Certain “knowledgeable
employees” within the meaning of Rule 3c-5 of the Investment Company Actalso participate in the Funds.

         The Firm, without notice to or consent of investors, has entered into, and may in the future enter
into, side letters with certain investors in the Funds (“Side Letters”). Side Letters may grant preferential
liquidity, transparency, reporting, fee or other terms. Fund investors that are c urrent and former Firm-

related personnel and affiliatesof the Firm have preferential liquidity rightsto the extent theGeneral Partner
of the Fund waives thenotice or other requirements for a redemptionspecified in the applicable governing
Fund documents in connection withsuch redemption, which occurs regularly, and, as disclosed above in Item
6, Unrestricted Withdrawals are permitted for certain investors funding capital commitments to certain
Deerfield Funds. Investors who or which redeem their investments ahead of other investorscould adversely
impact the remaining investors in the Fund. Similarly, where certain investors in a Fund have preferential
transparency rights, those investors would have information before other investors, which could benefit
those investors withsuch preferential transparency rights.
Sector Form 13F Holdings Value ($B)
Nuvalent Inc 1.8
UNUM Therapeutics Inc 0.3
Praxis Precision Medicines Inc 0.3
Upjohn Inc 0.3
United Therapeutics Corp 0.3
Revolution Medicines Inc 0.2
Celcuity Inc 0.2
Centene Corp 0.2
Zafgen Inc 0.2
Brookdale Senior Living Inc 0.2
View All
Holdings by Sector ($B)
10.08.06.04.02.00.02011201620212027
Type Form D Funds Date Sold AUM
HF Deerfield Healthcare Innovations Fund III-A LP [2024-02-20] 469.6 M 169.6 M
Filed 2024-11-01 (D/A) · Exemption 506(b), 3(c), 3(c)(7) · Remaining Indefinite · Duration One year or less · Revenue Decline to Disclose
HF Deerfield Healthcare Innovations Fund III LP [2024-02-20] 469.6 M 414.7 M
Filed 2024-11-01 (D/A) · Exemption 506(b), 3(c), 3(c)(7) · Remaining Indefinite · Duration One year or less · Revenue Decline to Disclose
HF Deerfield Private Design Fund V LP [2020-11-24] 1,340.5 M
Offered $2,500,000,000 · Filed 2020-07-31 (D) · Exemption 506(b), 3(c), 3(c)(7) · Remaining $2,500,000,000 · Duration One year or less · Revenue Not Applicable
HF Deerfield Healthcare Innovations Fund II LP [2019-08-29] 774.9 M
Offered $1,000,000,000 · Filed 2019-06-25 (D) · Exemption 506(b), 3(c), 3(c)(7) · Remaining $1,000,000,000 · Duration One year or less · Revenue Not Applicable
HF Deerfield Private Design Fund IV LP [2017-02-28] 2,391.8 M 3,851.0 M
Offered $2,500,000,000 · Filed 2016-11-25 (D) · Exemption 506(b), 3(c), 3(c)(7) · Minimum $300,000 · Remaining $108,250,000 · Duration One year or less · Revenue Not Applicable
HF Deerfield Healthcare Innovations Fund LP [2015-10-28] 550.0 M 1,800.3 M
Offered $550,000,000 · Filed 2015-07-28 (D) · Exemption 506(b), 3(c), 3(c)(7) · Minimum $200,000 · Duration One year or less · Revenue Not Applicable
HF Deerfield Private Design Fund III LP [2014-08-12] 1,532.2 M
Offered $1,600,000,000 · Filed 2014-04-02 (D) · Exemption 506(b), 3(c), 3(c)(7) · Remaining $1,600,000,000 · Duration One year or less · Revenue Not Applicable
HF Deerfield International Master Fund LP [2013-03-28] 2,009.8 M 1,284.9 M
Filed 2017-03-02 (D/A) · Exemption 506(b), 3(c), 3(c)(7) · Minimum $250,000 · Remaining Indefinite · Duration More than one year · Net Assets Decline to Disclose
PE Deerfield PDI Financing II LP 2013-03-28 35.3 M
HF Deerfield Private Design International II LP [2013-03-28] 270.6 M 80.3 M
Filed 2010-12-17 (D) · Exemption 506, 3(c), 3(c)(7) · Minimum $125,000 · Remaining Indefinite · Duration One year or less · Net Assets $25,000,001 - $50,000,000
View All
AUM Breakdown Accounts AUM ($B)
By Client Type
(a) Individuals (other than high net worth individuals) 0 0.0
(b) Individuals (high net worth individuals) 0 0.0
(c) Banking or thrift institutions 0 0.0
(d) Investment companies 0 0.0
(e) Business development companies 0 0.0
(f) Pooled investment vehicles 12 19.1
(g) Pension and profit sharing plans 0 0.0
(h) Charitable organizations 0 0.0
(i) State or municipal government entities 0 0.0
(j) Other investment advisers 0 0.0
(k) Insurance companies 0 0.0
(l) Sovereign wealth funds and foreign official institutions 0 0.0
(m) Corporations or other businesses not listed above 0 0.0
(n) Other 0 0.0
Total 12 19.1
By Discretionary
Discretionary 12 19.1
Non-Discretionary 0 0.0
Total 12 19.1
By Non-United States Persons
Non-United States Persons 0.1
United States Persons 19.0
Total 12 19.1
Form D Directors Role # Filings # Firms 2011 - 2026
Peter Young Director 116 22
Graham Cook Director 79 20
Nicholas Lane Director 13 5
James Flynn Director, Executive Officer 21 2
Deerfield Mgmt Hif III LP Promoter 2 1
Je Flynn Capital Hif III LLC Promoter 2 1
J E Flynn Capital III LLC Executive Officer 1 1
Deerfield Mgmt III LP Executive Officer 1 1
Deerfield Mgmt IV LP Executive Officer 1 1
Je Flynn Capital IV LLC Executive Officer 1 1
View All
EDGAR Form CIK 2011 - 2026
13F-HR [0001009258]
3 [0001009258]
4 [0001009258]
SC 13D [0001009258]
Form 13D/13G Filer Form 13D/13G Subject Filed
Deerfield Management Company LP Series C DA32 Life Science Tech Acquisition Corp [2021-08-10]
Deerfield Management Company LP Series C Deerfield Healthcare Technology Acquisitions Corp [2020-07-30]
Firm Profile (Form ADV)
Discretionary AUM$4.3B
ServesInstitutional
Fund TypesHedge Fund, Private Equity
LEI5493009YAY9MTF1EQS20
Form 3/4/5 Subject 2011 - 2026
Nuvalent Inc
Deerfield Management Company LP
Flynn James E
Deerfield Mgmt HIF LP
Deerfield Mgmt III LP
Parabilis Medicines Inc
Deerfield Private Design Fund III LP
Deerfield Healthcare Innovations Fund LP
Zafgen Inc
Deerfield Private Design Fund IV LP
View All
Insider Transaction (Form 3/4/5) Date Action Shares Price Value ($)
Zafgen Inc LRMR
Common Stock
2026-02-27 Buy 1,084,012 $5.00 5,420,060
Zafgen Inc LRMR
Common Stock
2026-02-27 Buy 831,978 $5.00 4,159,890
Zafgen Inc LRMR
Common Stock
2026-02-27 Buy 2,000,000 $5.00 10,000,000
Zafgen Inc LRMR
Common Stock
2026-02-27 Buy 1,084,010 $5.00 5,420,050
Nuvalent Inc NUVL
Class A Common Stock
2025-11-24 Sell 371,287 $95.45 35,439,344
Nuvalent Inc NUVL
Class A Common Stock
2025-11-24 Sell 371,287 $95.45 35,439,344
Zafgen Inc LRMR
Common Stock
2025-07-31 Buy 3,387,539 $3.20 10,840,125
Zafgen Inc LRMR
Common Stock
2025-07-31 Buy 2,599,932 $3.20 8,319,782
Zafgen Inc LRMR
Common Stock
2025-07-31 Buy 3,387,529 $3.20 10,840,093
ARS Pharmaceuticals Inc SPRY
Class A Common Stock
2025-06-27 Sell 370,074 $18.46 6,831,566
ARS Pharmaceuticals Inc SPRY
Class A Common Stock
2025-06-27 Sell 370,075 $18.46 6,831,584
Nuvalent Inc NUVL
Stock Option (Right to Buy) · derivative
2025-06-18 Grant 4,147 $0.00
Nuvalent Inc NUVL
Class A Common Stock
2025-06-18 Grant 2,647 $0.00
Nuvalent Inc NUVL
Class A Common Stock
2025-06-18 Grant 2,647 $0.00
Nuvalent Inc NUVL
Stock Option (Right to Buy) · derivative
2025-06-18 Grant 4,147 $0.00
Zafgen Inc LRMR
Stock Option (Right to Buy) · derivative
2025-05-13 Grant 19,000 $0.00
BiomX Inc PHGE
Warrants · derivative
2025-04-21 Grant 1,611,864
BiomX Inc PHGE
Warrants · derivative
2025-04-21 Grant 1,611,864
BiomX Inc PHGE
Stock Option (Right to Buy) · derivative
2025-04-14 Grant 17,600 $0.00
BiomX Inc PHGE
Warrants · derivative
2025-02-27 Grant 1,258,614
showing 20 of 200 most recent transactions
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