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Type	Result	AUM ($B)

Form 13F Holdings
Firm	Period	DFND	Voting	Shares
Nantahala Capital Management LLC	[2025-06-30]	SOLE	3,184,947	3,184,947
SilverArc Capital Management LLC	[2025-06-30]	SOLE	2,761,684	2,761,684
Alyeska Investment Group LP	[2025-06-30]	SOLE	2,643,445	2,643,445
AIGH Capital Management LLC	[2025-06-30]	SOLE	2,232,798	2,232,798
AIGH Capital Management LLC	[2025-06-30]	OTR	0	1,218,227
Vanguard Group Inc	[2025-06-30]	SOLE	0	1,172,365
Birchview Capital LP	[2025-06-30]	SOLE	1,159,059	1,159,059
Perkins Capital Management Inc	[2025-06-30]	SOLE	1,005,777	1,153,977
Knollwood Investment Advisory, LLC	[2025-06-30]	SOLE	0	1,034,617
Geode Capital Management LLC	[2025-06-30]	DFND	247,917	247,917
Kennedy Capital Management LLC	[2025-06-30]	SOLE	195,399	195,399
BlackRock, Inc.	[2025-06-30]	SOLE	95,968	95,968
Millennium Management LLC	[2025-06-30]	SOLE	43,356	43,356
Renaissance Technologies LLC	[2025-06-30]	SOLE	37,016	37,016
Arcus Capital Partners LLC	[2025-06-30]	SOLE	0	30,050
Qube Research & Technologies Ltd	[2025-06-30]	SOLE	29,034	29,034
Northern Trust Corp	[2025-06-30]	DFND	27,662	27,662
Bank of America Corp /DE/	[2025-06-30]	DFND	23,584	23,842
Verdence Capital Advisors LLC	[2025-06-30]	SOLE	17,410	17,410
Jane Street Group LLC	[2025-06-30]	DFND	15,481	15,481
XTX Topco Ltd	[2025-06-30]	DFND	14,012	14,012
Tufton Capital Management	[2025-06-30]	SOLE	0	13,700
State Street Corp	[2025-06-30]	DFND	11,969	11,969
Vanguard Group Inc	[2025-06-30]	DFND	0	8,140
Wells Fargo & Company/MN	[2025-06-30]	DFND	0	5,100
Tower Research Capital LLC (TRC)	[2025-06-30]	DFND	2,473	2,473
Morgan Stanley	[2025-06-30]	DFND	0	2,000
Raymond James Financial Inc	[2025-06-30]	DFND	0	1,100
BNP Paribas Financial Markets	[2025-06-30]	DFND	0	394
SBI Securities Co., Ltd.	[2025-06-30]	DFND	55	55
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