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Type	Result	AUM ($BB)

Form 13F Holdings
Firm	Period	DFND	Voting	Shares
BlackRock Inc.	[2023-03-31]	SOLE	3,692,239.0	3,775,353.0
Armistice Capital LLC	[2023-03-31]	SOLE	2,012,000.0	2,012,000.0
Farallon Capital Management LLC	[2023-03-31]	OTR	1,550,000.0	1,550,000.0
Vanguard Group Inc	[2023-03-31]	SOLE	0.0	1,500,967.0
State Street Corp	[2023-03-31]	DFND	1,150,899.0	1,200,936.0
Braidwell LP	[2023-03-31]	SOLE	1,038,310.0	1,038,310.0
Krensavage Asset Management LLC	[2023-03-31]	SOLE	603,301.0	603,301.0
Northern Trust Corp	[2023-03-31]	OTR	213,256.0	514,849.0
Dimensional Fund Advisors LP	[2023-03-31]	SOLE	485,526.0	512,808.0
Renaissance Technologies LLC	[2023-03-31]	SOLE	413,600.0	427,464.0
Geode Capital Management LLC	[2023-03-31]	DFND	395,076.0	395,076.0
Citadel Advisors LLC	[2023-03-31]	DFND	348,757.0	348,757.0
Northern Trust Corp	[2023-03-31]	DFND	144,161.0	348,467.0
Jacobs Levy Equity Management Inc	[2023-03-31]	SOLE	302,093.0	346,455.0
Invesco Ltd.	[2023-03-31]	DFND	0.0	301,770.0
UBS Asset Management Americas Inc	[2023-03-31]	SOLE	249,378.0	275,951.0
Pictet Asset Management Sa	[2023-03-31]	DFND	1.0	270,853.0
First Manhattan Co LLC	[2023-03-31]	SOLE	253,975.0	263,375.0
Goldman Sachs Group Inc	[2023-03-31]	DFND	219,690.0	230,090.0
Bank of America Corp /DE/	[2023-03-31]	DFND	4,458.0	222,708.0
Commodore Capital LP	[2023-03-31]	SOLE	217,253.0	217,253.0
Bank of New York Mellon Corp	[2023-03-31]	DFND	155,226.0	167,703.0
JPMorgan Chase & Co	[2023-03-31]	DFND	123,153.0	167,179.0
Price T Rowe Associates Inc /MD/	[2023-03-31]	SOLE	33,414.0	154,343.0
Charles Schwab Investment Management Inc	[2023-03-31]	SOLE	148,558.0	148,558.0
Millennium Management LLC	[2023-03-31]	SOLE	140,783.0	140,783.0
Morgan Stanley	[2023-03-31]	DFND	118,240.0	131,948.0
Principal Financial Group Inc	[2023-03-31]	DFND	121,603.0	121,603.0
FMR LLC	[2023-03-31]	DFND	119,766.0	120,101.0
Assenagon Asset Management S.A.	[2023-03-31]	SOLE	118,357.0	118,357.0
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