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Type	Result	AUM ($B)

Form 13F Holdings
Firm	Period	DFND	Voting	Shares
JW Asset Management LLC	[2025-06-30]	SOLE	3,092,485	3,092,485
RTW Investments LP	[2025-06-30]	SOLE	2,584,131	2,584,131
Brown Advisory Inc	[2025-06-30]	DFND	1,724,905	2,145,162
Nantahala Capital Management LLC	[2025-06-30]	SOLE	1,775,530	1,775,530
Findell Capital Management LLC	[2025-06-30]	SOLE	1,379,480	1,379,480
TYRO Capital Management LLC	[2025-06-30]	SOLE	1,066,721	1,066,721
Capital Research Global Investors	[2025-06-30]	DFND	1,024,417	1,024,417
BAMCO Inc /NY/	[2025-06-30]	DFND	0	907,537
William Blair Investment Management LLC	[2025-06-30]	SOLE	688,664	865,244
Morgan Stanley	[2025-06-30]	DFND	820,622	844,851
Rice Hall James & Associates LLC	[2025-06-30]	SOLE	663,271	837,707
Mudita Advisors LLP	[2025-06-30]	SOLE	600,664	600,664
Toronto Dominion Bank	[2025-06-30]	DFND	0	540,024
Boothbay Fund Management LLC	[2025-06-30]	OTR	0	537,513
Balyasny Asset Management LP	[2025-06-30]	SOLE	488,688	488,688
First Light Asset Management LLC	[2025-06-30]	SOLE	417,157	417,157
Royce & Associates LP	[2025-06-30]	SOLE	400,463	400,463
Centerbook Partners LP	[2025-06-30]	SOLE	379,385	379,385
JPMorgan Chase & Co	[2025-06-30]	DFND	325,671	373,112
Viking Global Investors LP	[2025-06-30]	SOLE	343,465	343,465
Affinity Asset Advisors LLC	[2025-06-30]	SOLE	334,863	334,863
Nuveen, LLC	[2025-06-30]	DFND	300,341	300,341
Pier Capital LLC	[2025-06-30]	SOLE	164,700	252,318
Kornitzer Capital Management Inc /KS	[2025-06-30]	SOLE	246,085	246,085
Granite Investment Partners LLC	[2025-06-30]	SOLE	232,700	232,700
Summit Partners Public Asset Management LLC	[2025-06-30]	SOLE	119,662	229,905
Woodson Capital Management LP	[2025-06-30]	SOLE	225,000	225,000
Soleus Capital Management LP	[2025-06-30]	SOLE	211,900	211,900
Raymond James Financial Inc	[2025-06-30]	DFND	124,882	186,524
Union Square Park Capital Management LLC	[2025-06-30]	SOLE	170,000	170,000
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