Perceptive Advisors LLC

ITEM 5: FEES AND COMPENSATION

The Advisor receives compensation for its advisory services, including management fees and performance-
based compensation, as set forth in the applicable governing documents of the funds and other investment
vehicles it advises. Fee structures vary depending on the applicable fund, vehicle, investor class and
strategy.

The Perceptive Life Sciences Funds

The Advisor receives a management fee (the “Management Fee”), payable at the feeder fund level,
calculated based on the net asset value of the Perceptive Life Sciences Funds. The Management Fee is
payable monthly at the beginning of each month. Management Fee calculation methodology is described
in detail in each feeder fund’s Governing Documents.

The Advisor, in its discretion, may waive all or any portion of the Management Fee for any investor and
may agree that a portion of its Management Fee be paid to third parties.

Each feeder fund also reimburses and/or advances to the Advisor a maximum of 1% per annum of the
average month-end net asset value of each feeder fund for certain of the Advisor’s administrative and
management costs and expenses, including without limitation computer equipment and services, office
space and utilities, salaries and bonuses, and other overhead expenses of the Advisor, except to the extent
such costs and expenses are provided through “soft dollars” as described in Item 12 herein. Certain
investors in the feeder funds hold shares or limited partnership interests that are not subject to this 1% fee.

Please see Item 6 for a discussion of the Advisor’s performance-based compensation.

The Credit Opportunities Funds

The Advisor receives a Management Fee, calculated and payable quarterly in advance. Management Fee
calculation methodology is described in detail in each Credit Opportunities Fund’s Governing Documents.

Please see Item 6 for a discussion of the Advisor’s performance-based compensation.

The Venture Funds

The Advisor receives a Management Fee, calculated and payable quarterly in advance. Management Fee
calculation methodology is described in detail in each Venture Fund’s Governing Documents.

Please see Item 6 for a discussion of the Advisor’s performance-based compensation.

The Capital Solutions Funds

The Advisor receives a Management Fee, calculated and payable quarterly in advance. Management Fee
calculation methodology is described in detail in the Capital Solutions Fund’s Governing Documents.

The Adviser, in its discretion, may waive a portion of the Management Fee in exchange for a reduction in
the Adviser’s cash capital contribution obligation and/or corresponding interest in the Capital Solutions
Funds’ profits.

Please see Item 6 for a discussion of the Advisor’s performance-based compensation.

The Advisor, in its discretion, may waive all or any portion of the Management Fee for any investor.
Generally 100% of the Life Sciences Funds’ the Credit Opportunity Funds’, the Venture Funds’ and Capital
Solutions Fund’s pro rata share of any amount of director’s fees, consulting fees, commitment fees, break-
up fees, monitoring fees, success fees or other remuneration paid to the general partner of the applicable
fund, the Advisor or any of the Advisor’s principals by or on behalf of portfolio companies, net of expenses,
will be treated as an offset against future Management Fees or will reduce Fund expenses; provided,
however, that the Management Fee will not be reduced below zero for the applicable fund. Generally, either
the Advisor bears the costs of any placement fees for its Funds, or any such fees offset the Management
Fee of the applicable fund.

Separate Account

The Separate Account is not charged any fees by the Advisor.

Co-investment Vehicles

The Advisor establishes specific fee schedules with respect to each co-investment vehicle. Fees on co-
investment vehicles may be greater than, equal to, or lower than, the fees applicable to the Client Accounts
alongside which co-investment vehicles participate in investment opportunities, and may include reduced
or no management fees, different carried interest or incentive allocations, and/or different expense
arrangements. The Advisor, in its sole discretion, may waive or lower the fees for some or all of the
investors in the co-investment vehicle. Such waiver or reduction of the fees will not result in any increase
in the fee or expense burden on other investors in the co-investment vehicles.

Expenses

Except as otherwise agreed with any particular Client Account in the relevant Governing Documents,
generally each Client Account is responsible for, among other things, all third-party costs and expenses
related to their investments and operations, including all expenses and costs incurred in investigating,
developing, negotiating, structuring, acquiring, trading, settling, monitoring and holding portfolio
investments and prospective portfolio investments (whether or not consummated); travel, legal, tax and

accounting expenses in connection therewith; broken deal expenses; costs and expenses related to a
potential investment idea, including expenses related thereto which may consist of reimbursement to the
Advisor for a portion of the compensation paid to an employee or consultant of the Advisor including an
entrepreneur-in-residence and an applicable portion of the overhead of the Advisor; expenses related to the
registration, qualification or exemption of any Fund under any applicable laws; brokerage fees and
commissions and prime brokerage fees, clearing and settlement charges, bank services fees, custodial
expenses, agent bank and other bank service fees and other investment costs; payments to legal counsel,
tax advisors, auditors, accountants, administrators, directors, appraisers, custodians, consultants and other
outside advisors; expenses of the advisory boards attributable to any of the Funds; insurance; market data
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ITEM 7: TYPES OF CLIENTS

The Advisor’s clients are the Funds, the Separate Account, and co-investment vehicles. Each Fund’s
Governing Documents specify the eligibility criteria and minimum investment requirements. Although the
Advisor has the authority to accept subscriptions of a lesser amount, the required minimum initial
investment in the Funds can range from $500,000 to $5,000,000 depending on the Fund.

Investors in the Client Accounts and co-investment vehicles consist primarily of institutional investors,
financial institutions, other investment funds, pension plans, endowments, foundations, family offices, and
high-net-worth individuals. The Advisor requires Fund investors and co-investors to make representations
concerning their financial sophistication, eligibility to invest, and ability to bear the risk of loss of their
entire investment. The Advisor may, in its discretion, accept investors on terms that differ from those
offered to other investors, including through side letters or other arrangements, as permitted by the relevant
Governing Documents.