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Type	Result	AUM ($B)

Form 13F Holdings
Firm	Period	DFND	Voting	Shares
RTW Investments LP	[2025-06-30]	SOLE	2,506,102	2,506,102
Propel Bio Management LLC	[2025-06-30]	DFND	801,557	1,791,557
Alta Fundamental Advisers LLC	[2025-06-30]	SOLE	1,398,977	1,398,977
BML Capital Management LLC	[2025-06-30]	SOLE	0	1,136,091
Simplify Asset Management Inc	[2025-06-30]	SOLE	990,000	990,000
Morgan Stanley	[2025-06-30]	DFND	817,821	820,421
Toronto Dominion Bank	[2025-06-30]	DFND	0	750,000
Lion Point Capital LP	[2025-06-30]	SOLE	548,806	548,806
Bleichroeder LP	[2025-06-30]	SOLE	500,000	500,000
UBS Group AG	[2025-06-30]	DFND	0	322,648
XTX Topco Ltd	[2025-06-30]	DFND	160,963	160,963
Valeo Financial Advisors LLC	[2025-06-30]	SOLE	130,699	130,699
Susquehanna International Group LLP	[2025-06-30]	OTR	63,369	126,069
Jane Street Group LLC	[2025-06-30]	DFND	31,933	120,033
Goldman Sachs Group Inc	[2025-06-30]	DFND	119,449	119,449
Cascades Capital Asset Management LLC	[2025-06-30]	SOLE	67,135	67,135
Northern Trust Corp	[2025-06-30]	DFND	53,001	53,001
Citadel Advisors LLC	[2025-06-30]	DFND	43,900	43,900
Raymond James Financial Inc	[2025-06-30]	DFND	0	43,235
Focus Partners Wealth	[2025-06-30]	SOLE	0	36,000
Royal Bank of Canada	[2025-06-30]	DFND	35,600	35,600
Group One Trading LLC	[2025-06-30]	SOLE	31,616	31,616
Safeguard Investment Advisory Group LLC	[2025-06-30]	SOLE	0	25,044
Creative Planning	[2025-06-30]	SOLE	0	23,410
Scientech Research LLC	[2025-06-30]	SOLE	19,064	19,064
National Bank of Canada /FI/	[2025-06-30]	DFND	0	18,700
State Street Corp	[2025-06-30]	DFND	18,246	18,246
Geode Capital Management LLC	[2025-06-30]	DFND	17,958	17,958
Walleye Capital LLC	[2025-06-30]	SOLE	15,109	15,109
Mercer Global Advisors Inc /ADV	[2025-06-30]	SOLE	0	15,100
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