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Type	Result	AUM ($B)

Form 13F Holdings
Firm	Period	DFND	Voting	Shares
NEA Management Company LLC	[2025-06-30]	DFND	1,625,678	1,625,678
Blue Owl Capital Holdings LP	[2025-06-30]	DFND	0	554,250
Aisling Capital Management LP	[2025-06-30]	SOLE	325,370	325,370
Vanguard Group Inc	[2025-06-30]	SOLE	0	272,833
Alyeska Investment Group LP	[2025-06-30]	SOLE	213,020	213,020
Geode Capital Management LLC	[2025-06-30]	DFND	95,768	95,768
LPL Financial LLC	[2025-06-30]	SOLE	0	73,747
Renaissance Technologies LLC	[2025-06-30]	SOLE	69,442	69,442
Jane Street Group LLC	[2025-06-30]	DFND	21,800	21,800
State Street Corp	[2025-06-30]	DFND	20,948	20,948
Creative Planning	[2025-06-30]	SOLE	0	17,312
Dimensional Fund Advisors LP	[2025-06-30]	SOLE	15,900	15,900
Matrix Asset Advisors Inc/Ny	[2025-06-30]	SOLE	0	15,000
Susquehanna International Group LLP	[2025-06-30]	OTR	12,437	12,437
Osaic Holdings Inc	[2025-06-30]	DFND	0	12,427
Northern Trust Corp	[2025-06-30]	DFND	10,857	10,857
Raymond James Financial Inc	[2025-06-30]	DFND	0	9,515
Tower Research Capital LLC (TRC)	[2025-06-30]	DFND	3,375	3,375
Vanguard Group Inc	[2025-06-30]	DFND	0	2,512
SBI Securities Co., Ltd.	[2025-06-30]	DFND	1,703	1,703
UBS Group AG	[2025-06-30]	DFND	1,600	1,600
Riggs Asset Managment Co. Inc.	[2025-06-30]	SOLE	0	1,200
Bank of America Corp /DE/	[2025-06-30]	DFND	1,025	1,114
BlackRock, Inc.	[2025-06-30]	SOLE	992	992
Morgan Stanley	[2025-06-30]	DFND	357	401
Wells Fargo & Company/MN	[2025-06-30]	DFND	0	232
JPMorgan Chase & Co	[2025-06-30]	DFND	215	215
Group One Trading LLC	[2025-06-30]	SOLE	178	178
Hilltop National Bank	[2025-06-30]	DFND	73	73
BNP Paribas Financial Markets	[2025-06-30]	DFND	0	23
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