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Type	Result	AUM ($B)

Form 13F Holdings
Firm	Period	DFND	Voting	Shares
Acorn Capital Advisors LLC	[2025-06-30]	SOLE	2,839,674	2,839,674
Citadel Advisors LLC	[2025-06-30]	DFND	1,089,310	1,089,310
Shay Capital LLC	[2025-06-30]	SOLE	782,046	782,046
Vanguard Group Inc	[2025-06-30]	SOLE	0	705,988
Cantor Fitzgerald L P	[2025-06-30]	DFND	0	669,539
Highbridge Capital Management LLC	[2025-06-30]	SOLE	0	663,607
Vestal Point Capital LP	[2025-06-30]	SOLE	635,000	635,000
BlackRock, Inc.	[2025-06-30]	SOLE	564,803	564,803
StepStone Group LP	[2025-06-30]	DFND	491,938	491,938
NEA Management Company LLC	[2025-06-30]	DFND	478,548	478,548
Affinity Asset Advisors LLC	[2025-06-30]	SOLE	347,990	347,990
Carlyle Group Inc.	[2025-06-30]	DFND	0	269,895
Deep Track Capital LP	[2025-06-30]	SOLE	180,510	180,510
Tang Capital Management LLC	[2025-06-30]	OTR	0	169,245
ProSight Management LP	[2025-06-30]	SOLE	159,692	159,692
Renaissance Technologies LLC	[2025-06-30]	SOLE	122,636	122,636
Aisling Capital Management LP	[2025-06-30]	SOLE	88,607	88,607
Geode Capital Management LLC	[2025-06-30]	DFND	84,895	84,895
Sphera Funds Management Ltd	[2025-06-30]	DFND	60,454	60,454
Nantahala Capital Management LLC	[2025-06-30]	SOLE	54,208	54,208
Aldebaran Capital LLC	[2025-06-30]	SOLE	44,173	44,173
Landscape Capital Management LLC	[2025-06-30]	DFND	30,843	30,843
Rangeley Capital LLC	[2025-06-30]	SOLE	29,902	29,902
Two Sigma Advisers LP	[2025-06-30]	SOLE	25,788	26,828
Two Sigma Investments LP	[2025-06-30]	SOLE	25,862	25,862
Bridgeway Capital Management LLC	[2025-06-30]	SOLE	25,000	25,000
Northern Trust Corp	[2025-06-30]	DFND	22,510	22,510
GSA Capital Partners LLP	[2025-06-30]	SOLE	21,765	21,765
Morgan Stanley	[2025-06-30]	DFND	16,701	16,701
Goldman Sachs Group Inc	[2025-06-30]	DFND	14,964	14,964
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