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Type	Result	AUM ($B)

Form 13F Holdings
Firm	Period	DFND	Voting	Shares
Tang Capital Management LLC	[2025-06-30]	OTR	0	6,000,000
Deep Track Capital LP	[2025-06-30]	SOLE	3,947,807	3,947,807
Morgan Stanley	[2025-06-30]	DFND	3,752,967	3,753,613
Vanguard Group Inc	[2025-06-30]	SOLE	0	2,982,841
Blue Owl Capital Holdings LP	[2025-06-30]	DFND	0	2,969,199
UBS Group AG	[2025-06-30]	DFND	2,646,556	2,646,556
Citadel Advisors LLC	[2025-06-30]	DFND	2,431,299	2,431,299
Woodline Partners LP	[2025-06-30]	SOLE	2,348,526	2,348,526
Madison Avenue Partners LP	[2025-06-30]	SOLE	2,230,012	2,230,012
TRV GP IV LLC	[2025-06-30]	SOLE	2,132,867	2,132,867
BlackRock, Inc.	[2025-06-30]	SOLE	2,088,416	2,130,519
JPMorgan Chase & Co	[2025-06-30]	DFND	1,958,433	1,958,433
Redmile Group LLC	[2025-06-30]	SOLE	1,632,577	1,632,577
Acadian Asset Management LLC	[2025-06-30]	DFND	1,630,413	1,630,413
Peapod Lane Capital LLC	[2025-06-30]	SOLE	713,644	893,730
Millennium Management LLC	[2025-06-30]	SOLE	850,474	850,474
Great Point Partners LLC	[2025-06-30]	SOLE	0	850,000
ProSight Management LP	[2025-06-30]	SOLE	837,400	837,400
Monaco Asset Management SAM	[2025-06-30]	SOLE	702,393	702,393
Goldman Sachs Group Inc	[2025-06-30]	DFND	595,768	596,698
Geode Capital Management LLC	[2025-06-30]	DFND	582,586	582,586
Bank of America Corp /DE/	[2025-06-30]	DFND	0	480,530
Two Sigma Advisers LP	[2025-06-30]	SOLE	428,600	455,200
XTX Topco Ltd	[2025-06-30]	DFND	429,010	429,010
Jane Street Group LLC	[2025-06-30]	DFND	323,412	323,412
Dimensional Fund Advisors LP	[2025-06-30]	SOLE	249,906	300,175
SEI Investments Co	[2025-06-30]	SOLE	297,291	297,291
Susquehanna International Group LLP	[2025-06-30]	OTR	169,986	288,286
ArrowMark Colorado Holdings LLC	[2025-06-30]	SOLE	281,189	281,189
Two Sigma Investments LP	[2025-06-30]	SOLE	278,158	278,158
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