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Type	Result	AUM ($BB)

Form 13F Holdings
Firm	Period	DFND	Voting	Shares
ARK Investment Management LLC	[2023-03-31]	SOLE	6,791,128.0	7,179,112.0
BlackRock Inc.	[2023-03-31]	SOLE	5,915,034.0	6,212,913.0
Vanguard Group Inc	[2023-03-31]	SOLE	0.0	5,564,669.0
State Street Corp	[2023-03-31]	DFND	5,146,891.0	5,275,841.0
JPMorgan Chase & Co	[2023-03-31]	DFND	3,625,961.0	4,057,312.0
Sumitomo Mitsui Trust Holdings, Inc.	[2023-03-31]	DFND	3,401,914.0	3,401,914.0
Nikko Asset Management Americas Inc	[2023-03-31]	SOLE	3,031,827.0	3,401,914.0
FMR LLC	[2023-03-31]	DFND	2,644,706.0	2,645,538.0
William Blair Investment Management LLC	[2023-03-31]	SOLE	1,775,125.0	2,054,521.0
Credit Suisse AG	[2023-03-31]	DFND	1,426,313.0	1,447,308.0
Citadel Advisors LLC	[2023-03-31]	DFND	1,234,728.0	1,234,728.0
Geode Capital Management LLC	[2023-03-31]	DFND	1,107,008.0	1,107,008.0
Tao Capital Management LP	[2023-03-31]	SOLE	828,815.0	828,815.0
Avidity Partners Management LP	[2023-03-31]	SOLE	819,000.0	819,000.0
Baillie Gifford & Co	[2023-03-31]	DFND	544,347.0	807,030.0
Fisher Asset Management LLC	[2023-03-31]	DFND	284,066.0	777,376.0
Bank of New York Mellon Corp	[2023-03-31]	DFND	719,052.0	768,186.0
Balyasny Asset Management LP	[2023-03-31]	SOLE	714,448.0	714,448.0
Casdin Capital LLC	[2023-03-31]	SOLE	700,000.0	700,000.0
Voloridge Investment Management LLC	[2023-03-31]	SOLE	682,650.0	682,650.0
Goldman Sachs Group Inc	[2023-03-31]	DFND	591,296.0	601,530.0
Bank of America Corp /DE/	[2023-03-31]	DFND	21,133.0	577,143.0
Morgan Stanley	[2023-03-31]	DFND	520,713.0	541,662.0
Northern Trust Corp	[2023-03-31]	DFND	31,580.0	519,876.0
Two Sigma Investments LP	[2023-03-31]	SOLE	491,432.0	491,432.0
Nordea Investment Management AB	[2023-03-31]	SOLE	0.0	489,354.0
Dimensional Fund Advisors LP	[2023-03-31]	SOLE	447,215.0	477,447.0
Rafferty Asset Management LLC	[2023-03-31]	SOLE	431,068.0	431,068.0
Charles Schwab Investment Management Inc	[2023-03-31]	SOLE	422,929.0	422,929.0
Price T Rowe Associates Inc /MD/	[2023-03-31]	SOLE	84,228.0	369,952.0
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