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Type	Result	AUM ($BB)

Form 13F Holdings
Firm	Period	DFND	Voting	Shares
Invesco Ltd.	[2023-03-31]	DFND	0.0	4,802,626.0
Capital World Investors	[2023-03-31]	DFND	4,665,869.0	4,665,869.0
BlackRock Inc.	[2023-03-31]	SOLE	3,967,917.0	4,381,747.0
FMR LLC	[2023-03-31]	DFND	2,989,400.0	3,074,069.0
Price T Rowe Associates Inc /MD/	[2023-03-31]	SOLE	400,847.0	2,406,073.0
Viking Global Investors LP	[2023-03-31]	SOLE	2,331,245.0	2,331,245.0
Credit Suisse AG	[2023-03-31]	DFND	2,165,496.0	2,202,229.0
Janus Henderson Group PLC	[2023-03-31]	DFND	0.0	1,871,042.0
Genesis Investment Management LLP	[2023-03-31]	SOLE	1,151,361.0	1,569,764.0
Segantii Capital Management Ltd	[2023-03-31]	SOLE	1,490,275.0	1,490,275.0
BAMCO Inc /NY/	[2023-03-31]	DFND	0.0	1,425,214.0
Wellington Management Group LLP	[2023-03-31]	DFND	0.0	1,315,045.0
State Street Corp	[2023-03-31]	DFND	923,582.0	1,285,889.0
Capital International, Inc./CA/	[2023-03-31]	DFND	1,145,610.0	1,145,610.0
Rock Springs Capital Management LP	[2023-03-31]	SOLE	1,059,700.0	1,059,700.0
Clearbridge Investments LLC	[2023-03-31]	SOLE	784,813.0	796,213.0
Segantii Capital Management Ltd	[2023-03-31]	DFND	788,000.0	788,000.0
Paradigm Biocapital Advisors LP	[2023-03-31]	SOLE	780,558.0	780,558.0
Legal & General Group Plc	[2023-03-31]	DFND	416,480.0	772,620.0
Capital International Investors	[2023-03-31]	DFND	716,698.0	716,698.0
SC CHINA HOLDING Ltd	[2023-03-31]	DFND	694,634.0	694,634.0
Vanguard Group Inc	[2023-03-31]	DFND	0.0	657,785.0
Gilder Gagnon Howe & Co LLC	[2023-03-31]	DFND	0.0	568,737.0
Citigroup Inc	[2023-03-31]	DFND	562,170.0	562,170.0
M&G Investment Management Ltd	[2023-03-31]	SOLE	528,677.0	528,677.0
Geode Capital Management LLC	[2023-03-31]	DFND	464,133.0	464,133.0
Tree Line Advisors Hong Kong Ltd	[2023-03-31]	SOLE	460,000.0	460,000.0
Vivo Capital LLC	[2023-03-31]	SOLE	416,640.0	416,640.0
FIL Ltd	[2023-03-31]	DFND	341,673.0	364,339.0
Woodline Partners LP	[2023-03-31]	SOLE	336,966.0	336,966.0
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