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Type	Result	AUM ($B)

Form 13F Holdings
Firm	Period	DFND	Voting	Shares
SilverArc Capital Management LLC	[2025-06-30]	SOLE	3,033,879	3,033,879
Renaissance Technologies LLC	[2025-06-30]	SOLE	1,327,100	1,327,100
Morgan Stanley	[2025-06-30]	DFND	471,082	1,314,116
ARK Investment Management LLC	[2025-06-30]	SOLE	1,072,776	1,072,776
Macquarie Group Ltd	[2025-06-30]	SOLE	1,020,000	1,020,000
Taylor Frigon Capital Management LLC	[2025-06-30]	SOLE	992,289	994,647
Rock Springs Capital Management LP	[2025-06-30]	SOLE	989,990	989,990
Northern Trust Corp	[2025-06-30]	DFND	889,716	889,716
Millennium Management LLC	[2025-06-30]	SOLE	395,748	395,748
Jane Street Group LLC	[2025-06-30]	DFND	393,191	393,191
State Street Corp	[2025-06-30]	DFND	351,179	351,179
Atom Investors LP	[2025-06-30]	SOLE	329,519	329,519
Citadel Advisors LLC	[2025-06-30]	DFND	325,554	325,554
Yelin Lapidot Holdings Management Ltd.	[2025-06-30]	DFND	318,852	318,852
UBS Group AG	[2025-06-30]	DFND	82,529	290,425
DAFNA Capital Management LLC	[2025-06-30]	SOLE	272,402	272,402
Squarepoint Ops LLC	[2025-06-30]	DFND	0	199,000
Rothschild Investment LLC	[2025-06-30]	SOLE	0	181,400
Two Sigma Investments LP	[2025-06-30]	SOLE	178,946	178,946
Two Sigma Advisers LP	[2025-06-30]	SOLE	156,184	163,484
Matrix Asset Advisors Inc/Ny	[2025-06-30]	SOLE	0	93,833
Schnieders Capital Management LLC	[2025-06-30]	SOLE	90,000	90,000
Goldman Sachs Group Inc	[2025-06-30]	DFND	87,511	87,511
Kingsview Wealth Management LLC	[2025-06-30]	SOLE	0	83,179
Eagle Rock Investment Company LLC	[2025-06-30]	SOLE	0	71,212
Raymond James Financial Inc	[2025-06-30]	DFND	0	67,041
	[2025-06-30]	SOLE	0	60,688
Stifel Financial Corp	[2025-06-30]	DFND	53,355	53,455
Geode Capital Management LLC	[2025-06-30]	DFND	50,395	50,395
Bank of America Corp /DE/	[2025-06-30]	DFND	5,770	43,658
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