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Type	Result	AUM ($B)

Form 13F Holdings
Firm	Period	DFND	Voting	Shares
BlackRock, Inc.	[2025-06-30]	SOLE	1,587,314	1,625,770
Armistice Capital LLC	[2025-06-30]	SOLE	1,600,000	1,600,000
Morgan Stanley	[2025-06-30]	DFND	1,480,974	1,520,217
Vanguard Group Inc	[2025-06-30]	SOLE	0	1,026,382
Soleus Capital Management LP	[2025-06-30]	SOLE	658,145	658,145
State Street Corp	[2025-06-30]	DFND	576,847	600,181
Capitolis Liquid Global Markets LLC	[2025-06-30]	SOLE	591,553	591,553
Geode Capital Management LLC	[2025-06-30]	DFND	415,607	415,607
Marshall Wace LLP	[2025-06-30]	OTR	0	368,950
Hillsdale Investment Management Inc	[2025-06-30]	SOLE	262,064	262,064
CM Management LLC	[2025-06-30]	SOLE	250,000	250,000
Assenagon Asset Management S.A.	[2025-06-30]	SOLE	240,005	240,005
Renaissance Technologies LLC	[2025-06-30]	SOLE	236,446	236,446
Jacobs Levy Equity Management Inc	[2025-06-30]	SOLE	212,521	215,633
Bank of America Corp /DE/	[2025-06-30]	DFND	2,883	187,621
Goldman Sachs Group Inc	[2025-06-30]	DFND	182,239	182,249
Qube Research & Technologies Ltd	[2025-06-30]	SOLE	171,424	171,424
GlobeFlex Capital L P	[2025-06-30]	SOLE	153,112	167,515
Connor Clark & Lunn Investment Management Ltd	[2025-06-30]	SOLE	148,183	148,183
Dimensional Fund Advisors LP	[2025-06-30]	SOLE	125,150	139,871
Zacks Investment Management	[2025-06-30]	SOLE	125,533	135,845
Northern Trust Corp	[2025-06-30]	DFND	133,748	133,822
OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AM	[2025-06-30]	DFND	104,890	104,890
Nuveen, LLC	[2025-06-30]	DFND	103,267	103,267
Wells Fargo & Company/MN	[2025-06-30]	DFND	9,106	98,844
LSV Asset Management	[2025-06-30]	SOLE	83,500	95,700
Bank of New York Mellon Corp	[2025-06-30]	DFND	86,985	93,035
Voya Investment Management LLC	[2025-06-30]	DFND	0	92,677
Los Angeles Capital Management LLC	[2025-06-30]	SOLE	1,083	82,348
Charles Schwab Investment Management Inc	[2025-06-30]	SOLE	77,491	77,491
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