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Type	Result	AUM ($BB)

Form 13F Holdings
Firm	Period	DFND	Voting	Shares
ARK Investment Management LLC	[2023-03-31]	SOLE	19,120,059.0	20,584,180.0
Vanguard Group Inc	[2023-03-31]	SOLE	0.0	15,808,173.0
BlackRock Inc.	[2023-03-31]	SOLE	10,469,204.0	11,442,420.0
Nikko Asset Management Americas Inc	[2023-03-31]	SOLE	5,208,843.0	8,033,788.0
Sumitomo Mitsui Trust Holdings, Inc.	[2023-03-31]	DFND	8,033,788.0	8,033,788.0
State Street Corp	[2023-03-31]	DFND	2,598,103.0	4,966,244.0
Baillie Gifford & Co	[2023-03-31]	DFND	3,447,867.0	4,221,770.0
State of Michigan Retirement System	[2023-03-31]	SOLE	3,833,000.0	3,833,000.0
Citadel Advisors LLC	[2023-03-31]	DFND	3,644,539.0	3,644,539.0
Renaissance Technologies LLC	[2023-03-31]	SOLE	3,369,500.0	3,369,500.0
Dimensional Fund Advisors LP	[2023-03-31]	SOLE	3,260,068.0	3,290,357.0
Two Sigma Investments LP	[2023-03-31]	SOLE	3,191,291.0	3,191,291.0
Federated Hermes Inc	[2023-03-31]	DFND	2,524,487.0	2,524,794.0
D. E. Shaw & Co., Inc.	[2023-03-31]	DFND	2,281,145.0	2,288,245.0
Himension Capital Singapore PTE Ltd	[2023-03-31]	SOLE	2,242,607.0	2,242,607.0
Susquehanna International Group LLP	[2023-03-31]	DFND	415,052.0	2,240,352.0
Millennium Management LLC	[2023-03-31]	SOLE	2,228,244.0	2,228,244.0
Geode Capital Management LLC	[2023-03-31]	DFND	2,225,969.0	2,225,969.0
Two Sigma Advisers LP	[2023-03-31]	SOLE	1,954,978.0	2,160,011.0
Voloridge Investment Management LLC	[2023-03-31]	SOLE	1,947,040.0	1,947,040.0
Morgan Stanley	[2023-03-31]	DFND	1,597,222.0	1,893,479.0
Credit Suisse AG	[2023-03-31]	DFND	1,617,575.0	1,662,287.0
UBS Group AG	[2023-03-31]	DFND	0.0	1,658,705.0
First Trust Advisors LP	[2023-03-31]	SOLE	1,615,142.0	1,615,142.0
Man Group plc	[2023-03-31]	DFND	1,188,819.0	1,188,819.0
Bank of America Corp /DE/	[2023-03-31]	DFND	241,498.0	1,139,395.0
Charles Schwab Investment Management Inc	[2023-03-31]	SOLE	1,084,680.0	1,084,680.0
Cubist Systematic Strategies, LLC	[2023-03-31]	DFND	0.0	842,649.0
Nuveen Asset Management LLC	[2023-03-31]	DFND	794,294.0	794,294.0
Goldman Sachs Group Inc	[2023-03-31]	DFND	731,199.0	763,104.0
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