Opaleye Management Inc

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Opaleye Management Inc
CRD #124513
SEC #801-78700
CIK #0001595855
AUM $639.6 M (2025-07-29)
Employees 3 (100% Investors, 0% Brokers)
Phone617-229-5085
AddressOne Boston Place
Boston, MA 02108
Source [IAPD] [EDGAR]
Total AUM ($M)
90072054036018002011201620212026
Sector Form 13F Holdings Value ($M)
Transdel Pharmaceuticals Inc 119.3
Eton Pharmaceuticals Inc 40.8
Immunome Inc 32.8
SANUWAVE Health Inc 32.2
Liquidia Corp 30.8
Codexis Inc 30.7
Rhythm Pharmaceuticals Inc 30.0
Manhattan Pharmaceuticals Inc 19.3
Ocular Therapeutix Inc 14.8
Arvinas Inc 12.4
View All
Holdings by Sector ($M)
80064048032016002014201820222026
Type Form D Funds Date Sold ($M) AUM ($M)
HF Opaleye LP [2013-10-09] 42.3 623.4
AUM Breakdown Accounts AUM ($M)
By Client Type
(a) Individuals (other than high net worth individuals) 0 0.0
(b) Individuals (high net worth individuals) 0 0.0
(c) Banking or thrift institutions 0 0.0
(d) Investment companies 0 0.0
(e) Business development companies 0 0.0
(f) Pooled investment vehicles 1 623.4
(g) Pension and profit sharing plans 0 0.0
(h) Charitable organizations 0 0.0
(i) State or municipal government entities 0 0.0
(j) Other investment advisers 1 16.2
(k) Insurance companies 0 0.0
(l) Sovereign wealth funds and foreign official institutions 0 0.0
(m) Corporations or other businesses not listed above 0 0.0
(n) Other 0 0.0
Total 2 639.6
By Discretionary
Discretionary 2 639.6
Non-Discretionary 0 0.0
Total 2 639.6
By Non-United States Persons
Non-United States Persons 0.0
United States Persons 639.6
Total 2 639.6
Form D Directors # Filings # Firms 2011 - 2025
James Silverman 3
RRC Management LLC 1
Opaleye Management Inc 1
Opaleye GP LLC 1
EDGAR Form CIK 2011 - 2025
13F-HR [0001595855]
3 [0001595855]
4 [0001595855]
SC 13D [0001595855]
SC 13G [0001595855]
Form 13D/13G Filer Form 13D/13G Subject Filed
Opaleye Management Inc Larimar Therapeutics Inc [2025-04-16]
Opaleye Management Inc Protara Therapeutics Inc [2024-11-18]
Opaleye Management Inc Codexis Inc [2024-07-12]
Opaleye Management Inc IBIO Inc [2024-04-08]
Opaleye Management Inc Jounce Therapeutics Inc [2024-02-09]
Opaleye Management Inc Context Therapeutics Inc [2024-01-05]
Opaleye Management Inc Jounce Therapeutics Inc [2023-04-12]
Opaleye Management Inc TELA Bio Inc [2022-06-10]
Opaleye Management Inc TELA Bio Inc [2022-06-03]
Opaleye Management Inc Larimar Therapeutics Inc [2022-02-18]
Opaleye Management Inc FS Development Corp [2021-01-08]
Opaleye Management Inc Infinity Pharmaceuticals Inc [2020-09-21]
Opaleye Management Inc Tracon Pharmaceuticals Inc [2020-09-01]
Opaleye Management Inc Cardiff Oncology Inc [2020-08-28]
Opaleye Management Inc Chimerix Inc [2020-08-21]
Opaleye Management Inc Adamas Pharmaceuticals Inc [2020-08-21]
Opaleye Management Inc Semler Scientific Inc [2020-03-30]
Opaleye Management Inc Cidara Therapeutics Inc [2020-02-21]
Opaleye Management Inc Artara Therapeutics Inc [2020-01-21]
Opaleye Management Inc SANUWAVE Health Inc [2020-01-21]
Opaleye Management Inc Aptose Biosciences Inc [2019-12-27]
Opaleye Management Inc Fortress Biotech Inc [2019-11-22]
Opaleye Management Inc EDAP TMS Sa [2019-11-07]
Opaleye Management Inc Stereotaxis Inc [2019-08-16]
Opaleye Management Inc Eton Pharmaceuticals Inc [2019-05-24]
Opaleye Management Inc Ocular Therapeutix Inc [2019-05-03]
Opaleye Management Inc Avenue Therapeutics Inc [2019-01-22]
Opaleye Management Inc Cerecor Inc [2018-10-03]
Opaleye Management Inc Imprimis Pharmaceuticals Inc [2018-09-07]
Opaleye Management Inc Fennec Pharmaceuticals Inc [2018-06-22]
Opaleye Management Inc Strongbridge Biopharma PLC [2018-06-22]
Opaleye Management Inc Cidara Therapeutics Inc [2018-06-04]
Opaleye Management Inc Axogen Inc [2018-02-09]
Opaleye Management Inc Inotek Pharmaceuticals Corp [2017-10-06]
Opaleye Management Inc Mirna Therapeutics Inc [2017-06-29]
Opaleye Management Inc Tonix Pharmaceuticals Holding Corp [2017-04-17]
Opaleye Management Inc Wafergen Bio-Systems Inc [2016-11-28]
Opaleye Management Inc Wafergen Bio-Systems Inc [2016-11-28]
Opaleye Management Inc Medgenics Inc [2016-04-21]
Opaleye Management Inc Protalix Biotherapeutics Inc [2015-11-23]
Opaleye Management Inc Intec Pharma Ltd [2015-08-14]
Opaleye Management Inc Axogen Corp [2015-05-29]
Opaleye Management Inc Trillium Therapeutics Inc [2015-02-23]
Opaleye Management Inc Imprimis Pharmaceuticals Inc [2014-09-05]
Opaleye Management Inc Recro Pharma Inc [2014-07-24]
Opaleye Management Inc InspireMD Inc [2014-01-16]
Form 3/4/5 Subject 2011 - 2025
Opaleye Management Inc.
Codexis Inc
Eton Pharmaceuticals, Inc.
Harrow Inc
SANUWAVE Health, Inc.
Protara Therapeutics, Inc.
Tracon Pharmaceuticals, Inc.
TELA Bio, Inc.
Ocular Therapeutix Inc
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