Opaleye Management Inc

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Assets, Funds, Holdings

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Opaleye Management Inc
CRD #124513
SEC #801-78700
CIK #0001595855
AUM $802.8 M (2026-02-19)
Employees 4 (100% Investors, 0% Brokers)
Phone617-229-5085
AddressOne Boston Place
Boston, MA 02108
Source [IAPD] [EDGAR]
Total AUM ($M)
90072054036018002010201520212027
Type Form D Funds Date Sold ($M) AUM ($M)
HF Opaleye LP [2013-10-09] 42.3 789.2
AUM Breakdown Accounts AUM ($M)
By Client Type
(a) Individuals (other than high net worth individuals) 0 0.0
(b) Individuals (high net worth individuals) 0 0.0
(c) Banking or thrift institutions 0 0.0
(d) Investment companies 0 0.0
(e) Business development companies 0 0.0
(f) Pooled investment vehicles 1 789.2
(g) Pension and profit sharing plans 0 0.0
(h) Charitable organizations 0 0.0
(i) State or municipal government entities 0 0.0
(j) Other investment advisers 0 0.0
(k) Insurance companies 0 0.0
(l) Sovereign wealth funds and foreign official institutions 0 0.0
(m) Corporations or other businesses not listed above 1 13.6
(n) Other 0 0.0
Total 2 802.8
By Discretionary
Discretionary 2 802.8
Non-Discretionary 0 0.0
Total 2 802.8
By Non-United States Persons
Non-United States Persons 13.6
United States Persons 789.2
Total 2 802.8
Form D Directors # Filings # Firms 2011 - 2025
James Silverman 3
RRC Management LLC 1
Opaleye Management Inc 1
Opaleye GP LLC 1
EDGAR Form CIK 2011 - 2025
13F-HR [0001595855]
3 [0001595855]
4 [0001595855]
SC 13D [0001595855]
SC 13G [0001595855]
Form 13D/13G Filer Form 13D/13G Subject Filed
Opaleye Management Inc Pasithea Therapeutics Corp [2026-04-08]
Opaleye Management Inc Q32 Bio Inc [2026-02-20]
Opaleye Management Inc Alpha Cognition Inc [2026-02-06]
Opaleye Management Inc Rezolute Inc [2025-12-19]
Opaleye Management Inc Karyopharm Therapeutics Inc [2025-10-17]
Opaleye Management Inc Alpha Cognition Inc [2025-10-03]
Opaleye Management Inc Larimar Therapeutics Inc [2025-04-16]
Opaleye Management Inc Protara Therapeutics Inc [2024-11-18]
Opaleye Management Inc Codexis Inc [2024-07-12]
Opaleye Management Inc IBIO Inc [2024-04-08]
View All
Form 3/4/5 Subject 2011 - 2025
Opaleye Management Inc.
Eton Pharmaceuticals, Inc.
Sol-Gel Technologies Ltd.
Alpha Cognition Inc.
SANUWAVE Health, Inc.
Harrow Inc
Codexis Inc
Protara Therapeutics, Inc.
Tracon Pharmaceuticals, Inc.
TELA Bio, Inc.
Ocular Therapeutix Inc
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