OrbiMed Advisors LLC

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OrbiMed Advisors LLC
CRD #118608
SEC #801-61046
CIK #0001491569, 0001055951
AUM 20.61 B (2026-03-25)
Employees 118 (73% Investors, 0% Brokers)
Phone212-739-6400
Address601 Lexington Avenue
New York, NY 10022
Source [IAPD] [EDGAR] [Website] [Twitter] [LinkedIn] [Facebook]
Total AUM ($B)
25201510502001200920182027
Sector Form 13F Holdings Value ($B)
Edgewise Therapeutics Inc 0.5
Imara Inc 0.3
Avita Medical Ltd 0.3
Mdxhealth Sa 0.3
Lilly Eli & Co 0.2
Boston Scientific Corp 0.1
Sionna Therapeutics Inc 0.1
Astrazeneca PLC 0.1
Myriad Genetics Inc 0.1
MBX Biosciences Inc 0.1
View All
Holdings by Sector ($B)
151296302011201620212027
Type Form D Funds Date Sold AUM
PE OrbiMed Royalty & Credit Opportunities V Offshore LP [2026-03-25] 1,243.5 M 788.6 M
Offered $1,750,000,000 · Filed 2025-05-06 (D/A) · Exemption 506(b), 3(c), 3(c)(7) · Remaining $506,475,000 · Duration One year or less · Revenue Not Applicable
Other OrbiMed Private Investments X LP [2026-02-25] 1,572.9 M
Offered $1,750,000,000 · Filed 2025-09-29 (D) · Exemption 506(b), 3(c), 3(c)(7) · Remaining $1,750,000,000 · Duration One year or less · Revenue Not Applicable
PE OrbiMed Royalty & Credit Opportunities V LP [2026-02-25] 1,243.5 M 1,128.1 M
Offered $1,750,000,000 · Filed 2025-05-06 (D/A) · Exemption 506(b), 3(c), 3(c)(7) · Remaining $506,475,000 · Duration One year or less · Revenue Not Applicable
PE OrbiMed Royalty & Credit Opportunities IV Offshore LP [2023-02-28] 344.5 M 567.9 M
Offered $500,000,000 · Filed 2022-12-16 (D/A) · Exemption 506(b), 3(c), 3(c)(7) · Remaining $155,549,600 · Duration One year or less · Revenue Not Applicable
HF OrbiMed Partners SPV Ltd 2022-11-14 102.5 M
Other OrbiMed Asia Partners V LP [2022-08-03] 651.9 M 947.9 M
Offered $1,100,000,000 · Filed 2022-11-28 (D/A) · Exemption 506(b), 3(c), 3(c)(7) · Remaining $448,127,986 · Duration One year or less · Revenue Not Applicable
Other OrbiMed Private Investments IX LP [2022-08-03] 1,849.5 M 2,190.7 M
Offered $1,900,000,000 · Filed 2023-04-28 (D/A) · Exemption 506(b), 3(c), 3(c)(7) · Remaining $50,450,000 · Duration More than one year · Revenue Not Applicable
PE OrbiMed Royalty & Credit Opportunities IV LP [2022-08-03] 1,153.1 M 1,417.7 M
Offered $1,750,000,000 · Filed 2022-12-16 (D/A) · Exemption 506(b), 3(c), 3(c)(7) · Remaining $596,875,400 · Duration One year or less · Revenue Not Applicable
Other OrbiMed Private Investments VIII LP [2020-11-25] 1,683.2 M
Offered $1,400,000,000 · Filed 2020-08-27 (D) · Exemption 506(b), 3(c), 3(c)(7) · Remaining $1,400,000,000 · Duration One year or less · Revenue Not Applicable
HF OrbiMed New Horizons Master Fund LP [2020-08-21] 86.7 M 13.6 M
Filed 2023-04-14 (D/A) · Exemption 506(b), 3(c), 3(c)(7) · Minimum $100,000 · Remaining Indefinite · Duration More than one year · Net Assets Decline to Disclose
View All
AUM Breakdown Accounts AUM ($B)
By Client Type
(a) Individuals (other than high net worth individuals) 0 0.0
(b) Individuals (high net worth individuals) 0 0.0
(c) Banking or thrift institutions 0 0.0
(d) Investment companies 0 0.0
(e) Business development companies 0 0.0
(f) Pooled investment vehicles 32 20.6
(g) Pension and profit sharing plans 0 0.0
(h) Charitable organizations 0 0.0
(i) State or municipal government entities 0 0.0
(j) Other investment advisers 0 0.0
(k) Insurance companies 0 0.0
(l) Sovereign wealth funds and foreign official institutions 0 0.0
(m) Corporations or other businesses not listed above 0 0.0
(n) Other 0 0.0
Total 32 20.6
By Discretionary
Discretionary 32 20.6
Non-Discretionary 0 0.0
Total 32 20.6
By Non-United States Persons
Non-United States Persons 10.2
United States Persons 10.4
Total 32 20.6
Limited Partners2011 - 2026
California State Teachers' Retirement System
Oregon Public Employees Retirement Fund
Form D Directors Role # Filings # Firms 2011 - 2026
Brian Burkholder Director 71 22
John Collis Director 97 14
David Wang Director 40 7
Jonathan Wang Director 42 4
Samuel Isaly Director, Executive Officer, Promoter 21 3
Carl Gordon Director, Executive Officer 112 2
Peter Thompson Executive Officer 61 2
Jonathan Silverstein Director, Executive Officer 57 2
David Bonita Executive Officer 55 2
Sven Borho Director, Executive Officer 27 2
View All
EDGAR Form CIK 2011 - 2026
13F-HR [0001055951]
3 [0001055951]
4 [0001055951]
SC 13D [0001055951]
SC 13G [0001055951]
3 [0001491569]
4 [0001491569]
Form 13D/13G Filer Form 13D/13G Subject Filed
OrbiMed Advisors LLC Xilio Therapeutics Inc [2026-05-15]
OrbiMed Advisors LLC InspireMD Inc [2026-02-17]
OrbiMed Advisors LLC Cybin Inc [2026-02-17]
OrbiMed Advisors LLC Vistagen Therapeutics Inc [2025-11-14]
OrbiMed Advisors LLC CytomX Therapeutics Inc [2025-08-14]
OrbiMed Advisors LLC Whitehawk Therapeutics Inc [2025-05-15]
OrbiMed Advisors LLC ADC Therapeutics Sa [2025-02-14]
OrbiMed Advisors LLC RAPT Therapeutics Inc [2025-02-14]
OrbiMed Advisors LLC Forte Biosciences Inc [2025-02-14]
OrbiMed Advisors LLC Sionna Therapeutics Inc [2025-02-13]
OrbiMed Advisors LLC Corbus Pharmaceuticals Holdings Inc [2024-11-14]
OrbiMed Advisors LLC Avalo Therapeutics Inc [2024-11-14]
OrbiMed Advisors LLC C4 Therapeutics Inc [2024-11-14]
OrbiMed Advisors LLC Lomond Therapeutics Holdings Inc [2024-11-08]
OrbiMed Advisors LLC Upstream Bio Inc [2024-10-17]
OrbiMed Advisors LLC Traws Pharma Inc [2024-09-23]
OrbiMed Advisors LLC MBX Biosciences Inc [2024-09-23]
OrbiMed Advisors LLC Q32 Bio Inc [2024-03-28]
OrbiMed Advisors LLC InspireMD Inc [2024-02-14]
OrbiMed Advisors LLC Elevation Oncology Inc [2024-02-14]
OrbiMed Advisors LLC Scholar Rock Holding Corp [2024-02-14]
OrbiMed Advisors LLC Arrivent Biopharma Inc [2024-02-05]
OrbiMed Advisors LLC Turnstone Biologics Corp [2023-07-24]
OrbiMed Advisors LLC VectivBio Holding AG [2023-05-24]
OrbiMed Advisors LLC Apollomics Inc [2023-04-12]
OrbiMed Advisors LLC Gracell Biotechnologies Inc [2023-03-31]
OrbiMed Advisors LLC Enliven Therapeutics Inc [2023-02-28]
OrbiMed Advisors LLC Verastem Inc [2023-02-14]
OrbiMed Advisors LLC ALX Oncology Holdings Inc [2023-02-14]
OrbiMed Advisors LLC Kezar Life Sciences Inc [2023-02-14]
OrbiMed Advisors LLC Mersana Therapeutics Inc [2023-02-14]
OrbiMed Advisors LLC Third Harmonic Bio Inc [2022-09-28]
OrbiMed Advisors LLC Catalyst Biosciences Inc [2022-02-11]
OrbiMed Advisors LLC Gracell Biotechnologies Inc [2022-02-11]
OrbiMed Advisors LLC Jounce Therapeutics Inc [2022-02-11]
OrbiMed Advisors LLC Protara Therapeutics Inc [2022-02-11]
OrbiMed Advisors LLC Rxsight Inc [2022-02-11]
OrbiMed Advisors LLC Sonendo Inc [2022-02-11]
OrbiMed Advisors LLC VectivBio Holding AG [2022-02-11]
OrbiMed Advisors LLC Theseus Pharmaceuticals Inc [2021-10-19]
OrbiMed Advisors LLC Janux Therapeutics Inc [2021-06-22]
OrbiMed Advisors LLC Neuropace Inc [2021-04-29]
OrbiMed Advisors LLC VectivBio Holding AG [2021-04-20]
OrbiMed Advisors LLC Ikena Oncology Inc [2021-04-15]
OrbiMed Advisors LLC Edgewise Therapeutics Inc [2021-04-08]
OrbiMed Advisors LLC Decibel Therapeutics Inc [2021-03-02]
OrbiMed Advisors LLC Terns Pharmaceuticals Inc [2021-02-23]
OrbiMed Advisors LLC Gemini Therapeutics Inc /DE [2021-02-22]
OrbiMed Advisors LLC Vistagen Therapeutics Inc [2021-02-12]
OrbiMed Advisors LLC Larimar Therapeutics Inc [2021-02-12]
OrbiMed Advisors LLC Forte Biosciences Inc [2021-02-12]
OrbiMed Advisors LLC Mereo Biopharma Group PLC [2021-02-12]
OrbiMed Advisors LLC Otonomy Inc [2021-02-12]
OrbiMed Advisors LLC Strongbridge Biopharma PLC [2021-02-12]
OrbiMed Advisors LLC Theravance Biopharma Inc [2021-02-12]
OrbiMed Advisors LLC Gracell Biotechnologies Inc [2021-01-21]
OrbiMed Advisors LLC Kinnate Biopharma Inc [2020-12-11]
OrbiMed Advisors LLC Silverback Therapeutics Inc [2020-12-11]
OrbiMed Advisors LLC Galecto Inc [2020-11-06]
OrbiMed Advisors LLC PMV Pharmaceuticals Inc [2020-10-05]
OrbiMed Advisors LLC Graybug Vision Inc [2020-10-05]
OrbiMed Advisors LLC Prelude Therapeutics Inc [2020-10-05]
OrbiMed Advisors LLC Acutus Medical Inc [2020-08-18]
OrbiMed Advisors LLC Pandion Therapeutics Inc [2020-07-28]
OrbiMed Advisors LLC Fusion Pharmaceuticals Inc [2020-07-07]
OrbiMed Advisors LLC Compass Therapeutics Inc [2020-06-29]
OrbiMed Advisors LLC Repare Therapeutics Inc [2020-06-26]
OrbiMed Advisors LLC Oric Pharmaceuticals Inc [2020-05-01]
OrbiMed Advisors LLC Keros Therapeutics Inc [2020-04-17]
OrbiMed Advisors LLC Imara Inc [2020-03-20]
OrbiMed Advisors LLC Passage Bio Inc [2020-03-09]
OrbiMed Advisors LLC Krystal Biotech Inc [2020-02-14]
OrbiMed Advisors LLC Krystal Biotech Inc [2020-02-14]
OrbiMed Advisors LLC Applied Therapeutics Inc [2020-02-14]
OrbiMed Advisors LLC Prothena Corp PLC [2020-02-14]
OrbiMed Advisors LLC Crinetics Pharmaceuticals Inc [2020-02-14]
OrbiMed Advisors LLC Adverum Biotechnologies Inc [2020-02-14]
OrbiMed Advisors LLC MeiraGTx Holdings PLC [2020-02-14]
OrbiMed Advisors LLC Arcutis Biotherapeutics Inc [2020-02-10]
OrbiMed Advisors LLC Sierra Oncology Inc [2019-11-27]
OrbiMed Advisors LLC TELA Bio Inc [2019-11-25]
OrbiMed Advisors LLC 89bio Inc [2019-11-25]
OrbiMed Advisors LLC ESSA Pharma Inc [2019-11-12]
OrbiMed Advisors LLC Springworks Therapeutics Inc [2019-09-25]
OrbiMed Advisors LLC Bellus Health Inc [2019-09-18]
OrbiMed Advisors LLC Prevail Therapeutics Inc [2019-06-27]
OrbiMed Advisors LLC NextCure Inc [2019-05-21]
OrbiMed Advisors LLC Turning Point Therapeutics Inc [2019-04-24]
OrbiMed Advisors LLC X4 Pharmaceuticals Inc [2019-04-19]
OrbiMed Advisors LLC Avedro Inc [2019-02-28]
OrbiMed Advisors LLC Harpoon Therapeutics Inc [2019-02-21]
OrbiMed Advisors LLC Alector Inc [2019-02-20]
OrbiMed Advisors LLC Clovis Oncology Inc [2019-02-13]
OrbiMed Advisors LLC Deciphera Pharmaceuticals Inc [2019-02-13]
OrbiMed Advisors LLC Inspire Medical Systems Inc [2019-02-13]
OrbiMed Advisors LLC Synthorx Inc [2018-12-20]
OrbiMed Advisors LLC LogicBio Therapeutics Inc [2018-11-01]
OrbiMed Advisors LLC Arvinas Inc [2018-10-10]
OrbiMed Advisors LLC Principia Biopharma Inc [2018-09-27]
OrbiMed Advisors LLC Realm Therapeutics PLC [2018-08-15]
OrbiMed Advisors LLC Crinetics Pharmaceuticals Inc [2018-07-30]
OrbiMed Advisors LLC Tricida Inc [2018-07-11]
OrbiMed Advisors LLC Sierra Oncology Inc [2018-02-13]
OrbiMed Advisors LLC ARMO Biosciences Inc [2018-02-08]
OrbiMed Advisors LLC Restorbio Inc [2018-02-02]
OrbiMed Advisors LLC Kala Pharmaceuticals Inc [2018-01-12]
OrbiMed Advisors LLC scPharmaceuticals Inc [2017-12-01]
OrbiMed Advisors LLC Arsanis Inc [2017-11-30]
OrbiMed Advisors LLC Rhythm Pharmaceuticals Inc [2017-10-20]
OrbiMed Advisors LLC Synlogic Inc [2017-09-07]
OrbiMed Advisors LLC Clementia Pharmaceuticals Inc [2017-08-11]
OrbiMed Advisors LLC Alpine Immune Sciences Inc [2017-08-03]
OrbiMed Advisors LLC CTI Biopharma Corp [2017-06-15]
OrbiMed Advisors LLC Xtant Medical Holdings Inc [2017-05-30]
OrbiMed Advisors LLC Verona Pharma PLC [2017-05-08]
OrbiMed Advisors LLC Aerpio Pharmaceuticals Inc [2017-03-27]
OrbiMed Advisors LLC Newlink Genetics Corp [2017-02-13]
OrbiMed Advisors LLC Cellectis Sa [2017-02-13]
OrbiMed Advisors LLC Inotek Pharmaceuticals Corp [2017-02-13]
OrbiMed Advisors LLC Lion Biotechnologies Inc [2017-02-13]
OrbiMed Advisors LLC Obseva Sa [2017-02-03]
OrbiMed Advisors LLC ViewRay Inc [2016-08-26]
OrbiMed Advisors LLC SteadyMed Ltd [2016-08-12]
OrbiMed Advisors LLC Selecta Biosciences Inc [2016-07-07]
OrbiMed Advisors LLC Intellia Therapeutics Inc [2016-05-20]
OrbiMed Advisors LLC Aeglea Biotherapeutics Inc [2016-04-18]
OrbiMed Advisors LLC Corvus Pharmaceuticals Inc [2016-04-01]
OrbiMed Advisors LLC Immunomedics Inc [2016-02-16]
OrbiMed Advisors LLC ProNAi Therapeutics Inc [2016-02-16]
OrbiMed Advisors LLC Dynavax Technologies Corp [2016-02-16]
OrbiMed Advisors LLC Ehealth Inc [2016-02-16]
OrbiMed Advisors LLC Glaukos Corp [2016-02-12]
OrbiMed Advisors LLC Achillion Pharmaceuticals Inc [2016-02-12]
OrbiMed Advisors LLC Assembly Biosciences Inc [2016-02-12]
OrbiMed Advisors LLC Connecture Inc [2016-02-12]
OrbiMed Advisors LLC Immunogen Inc [2016-02-12]
OrbiMed Advisors LLC Insmed Inc [2016-02-12]
OrbiMed Advisors LLC Insys Therapeutics Inc [2016-02-12]
OrbiMed Advisors LLC Magellan Health Inc [2016-02-11]
OrbiMed Advisors LLC Ophthotech Corp [2016-02-11]
OrbiMed Advisors LLC PUMA Biotechnology Inc [2016-02-11]
OrbiMed Advisors LLC Dimension Therapeutics Inc [2015-11-06]
OrbiMed Advisors LLC Nabriva Therapeutics AG [2015-10-02]
OrbiMed Advisors LLC Pieris Pharmaceuticals Inc [2015-07-09]
OrbiMed Advisors LLC Cynapsus Therapeutics Inc [2015-07-02]
OrbiMed Advisors LLC Biotie Therapies Corp [2015-06-26]
OrbiMed Advisors LLC Adaptimmune Therapeutics PLC [2015-05-15]
OrbiMed Advisors LLC Synergy Pharmaceuticals Inc [2015-03-09]
OrbiMed Advisors LLC Neurocrine Biosciences Inc [2015-02-17]
OrbiMed Advisors LLC Sientra Inc [2015-02-17]
OrbiMed Advisors LLC Tornier NV [2015-02-17]
OrbiMed Advisors LLC Sinovac Biotech Ltd [2015-02-17]
OrbiMed Advisors LLC Proqr Therapeutics NV [2015-02-17]
OrbiMed Advisors LLC Molina Healthcare Inc [2015-02-17]
OrbiMed Advisors LLC Ironwood Pharmaceuticals Inc [2015-02-17]
OrbiMed Advisors LLC Cerus Corp [2015-02-17]
OrbiMed Advisors LLC Array Biopharma Inc [2015-02-17]
OrbiMed Advisors LLC Ascendis Pharma A/S [2015-02-12]
OrbiMed Advisors LLC Affimed NV [2014-09-19]
OrbiMed Advisors LLC Otonomy Inc [2014-08-22]
OrbiMed Advisors LLC Loxo Oncology Inc [2014-08-08]
OrbiMed Advisors LLC ROKA Bioscience Inc [2014-07-25]
OrbiMed Advisors LLC Mirati Therapeutics Inc [2014-02-14]
OrbiMed Advisors LLC Arqule Inc [2014-02-13]
OrbiMed Advisors LLC Acceleron Pharma Inc [2014-02-13]
OrbiMed Advisors LLC Insulet Corp [2014-02-13]
OrbiMed Advisors LLC Bacterin International Holdings Inc [2014-02-13]
OrbiMed Advisors LLC Mei Pharma Inc [2014-02-13]
OrbiMed Advisors LLC Intermune Inc [2014-02-13]
OrbiMed Advisors LLC Impax Laboratories Inc [2014-02-13]
OrbiMed Advisors LLC Arrowhead Research Corp [2014-02-13]
OrbiMed Advisors LLC Prothena Corp PLC [2014-02-13]
OrbiMed Advisors LLC Durata Therapeutics Inc [2014-02-13]
OrbiMed Advisors LLC Relypsa Inc [2013-12-02]
OrbiMed Advisors LLC Ambit Biosciences Corp [2013-05-30]
OrbiMed Advisors LLC InspireMD Inc [2013-04-23]
OrbiMed Advisors LLC InspireMD Inc [2013-04-22]
OrbiMed Advisors LLC 3SBIO Inc [2013-04-08]
OrbiMed Advisors LLC Fluidigm Corp [2013-02-14]
OrbiMed Advisors LLC Uroplasty Inc [2013-02-14]
OrbiMed Advisors LLC Xenoport Inc [2013-02-14]
OrbiMed Advisors LLC Map Pharmaceuticals Inc [2013-02-14]
OrbiMed Advisors LLC Infinity Pharmaceuticals Inc [2013-02-14]
OrbiMed Advisors LLC Natus Medical Inc [2013-02-14]
OrbiMed Advisors LLC Neurocrine Biosciences Inc [2013-02-14]
OrbiMed Advisors LLC Anthera Pharmaceuticals Inc [2013-02-11]
OrbiMed Advisors LLC Intercept Pharmaceuticals Inc [2012-10-26]
OrbiMed Advisors LLC Supernus Pharmaceuticals Inc [2012-05-14]
OrbiMed Advisors LLC Celsion Corp [2012-02-14]
OrbiMed Advisors LLC Pernix Therapeutics Holdings Inc [2012-02-14]
OrbiMed Advisors LLC Sequenom Inc [2012-02-14]
OrbiMed Advisors LLC Vivus Inc [2012-02-14]
OrbiMed Advisors LLC Orasure Technologies Inc [2012-02-14]
Firm Profile (Form ADV)
Discretionary AUM$6.7B
ServesInstitutional
Fund TypesHedge Fund, Private Equity
LEI57G4FX4JA0RP0CHYJ782
Related People Network
43 people file Form D offerings alongside this firm's people.
Form 3/4/5 Subject 2011 - 2026
Sionna Therapeutics Inc
OrbiMed Advisors LLC
OrbiMed Capital GP VIII LLC
OrbiMed Genesis GP LLC
OrbiMed Capital GP VII LLC
Enliven Therapeutics Inc
Shattuck Labs Inc
OrbiMed Capital GP IX LLC
Q32 Bio Inc
Traws Pharma Inc
View All
Insider Transaction (Form 3/4/5) Date Action Shares Price Value ($)
Sionna Therapeutics Inc SION
Common Stock
2026-02-03 Sell 29,063 $44.58 1,295,629
Sionna Therapeutics Inc SION
Common Stock
2026-02-02 Sell 1,890 $44.57 84,237
Sionna Therapeutics Inc SION
Common Stock
2025-12-24 Sell 33,356 $44.55 1,486,010
Sionna Therapeutics Inc SION
Common Stock
2025-12-19 Sell 875 $44.49 38,929
Sionna Therapeutics Inc SION
Common Stock
2025-12-18 Sell 100 $44.49 4,449
Sionna Therapeutics Inc SION
Common Stock
2025-12-17 Sell 900 $44.50 40,050
Sionna Therapeutics Inc SION
Common Stock
2025-11-26 Sell 1,600 $44.49 71,184
Sionna Therapeutics Inc SION
Common Stock
2025-11-25 Sell 11,890 $44.60 530,294
Sionna Therapeutics Inc SION
Common Stock
2025-11-24 Sell 94,583 $44.54 4,212,727
Keros Therapeutics Inc KROS
Common Stock
2025-11-21 Disposed to issuer 74,465 $17.75 1,321,754
Keros Therapeutics Inc KROS
Common Stock
2025-11-21 Disposed to issuer 140,057 $17.75 2,486,012
PMV Pharmaceuticals Inc PMVP
Common Stock
2025-10-23 Sell 1,000,000 $1.52 1,520,000
Adicet Bio Inc ACET
Common Stock
2025-10-08 Buy 3,500,000 $1.00 3,500,000
Adicet Bio Inc ACET
Common Stock
2025-10-08 Buy 1,500,000 $1.00 1,500,000
Turnstone Biologics Corp TSBX
Common Stock
2025-08-08 Tender 3,099,265
ImageneBio Inc IKNA
Common Stock
2025-07-25 Grant 83,611 $2.49 208,191
Corvus Pharmaceuticals Inc CRVS
Common Warrants (right to buy) · derivative
2025-06-27 Option exercise 1,397,684 $0.00
Corvus Pharmaceuticals Inc CRVS
Common Stock
2025-06-27 Option exercise 1,397,684 $3.50 4,891,894
Corvus Pharmaceuticals Inc CRVS
Common Stock
2025-06-27 Sell 1,176,332 $4.16 4,893,541
Passage Bio Inc PASG
Common Stock
2025-06-26 Sell 213,257 $0.33 70,375
showing 20 of 200 most recent transactions
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