Karyopharm Therapeutics Inc

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Karyopharm Therapeutics Inc
TickerKPTI
CIK #0001503802
CUSIP48576U205
SectorLife Sciences - Pharmaceutical Preparations
Address2 Mercer Road, Natick, MA 01760
Source [EDGAR]
Reg D Offering (Form D) Filed Raised Terms
Karyopharm Therapeutics Inc 2022-12-08 165.0 M Exemption: 506(b) · Duration: One year or less · Commission: $9,900,000 · Revenue: Decline to Disclose
CIK Filing 2011 - 2026
[0001503802] 10-K
[0001503802] 10-Q
[0001503802] 3
[0001503802] 4
[0001503802] 5
[0001503802] 8-K
[0001503802] D
[0001503802] SC 13D
[0001503802] SC 13G
Form 13D/13G Filer Form 13D/13G Subject Filed % Owned
Acorn BioVentures LP Karyopharm Therapeutics Inc [2026-05-15] 0.0
Ikarian Capital LLC Karyopharm Therapeutics Inc [2026-05-15] 0.0
Adage Capital Management LP Karyopharm Therapeutics Inc [2026-05-13] 0.0
Goldman Sachs Group Inc Karyopharm Therapeutics Inc [2026-05-12] 0.0
RA Capital Management LP Karyopharm Therapeutics Inc [2026-04-02] 0.0
Commodore Capital LP Karyopharm Therapeutics Inc [2026-04-02] 0.0
Integrated Core Strategies US LLC Karyopharm Therapeutics Inc [2026-02-10] 0.0
Opaleye Management Inc Karyopharm Therapeutics Inc [2025-10-17] 0.0
T Rowe Price Investment Management Inc Karyopharm Therapeutics Inc [2025-08-14] 0.0
JPMorgan Chase & Co Karyopharm Therapeutics Inc [2025-07-16] 0.0
Affinity Asset Advisors LLC Karyopharm Therapeutics Inc [2025-04-10] 0.0
Adage Capital Management LP Karyopharm Therapeutics Inc [2025-02-12] 0.0
Highbridge Capital Management LLC Karyopharm Therapeutics Inc [2024-10-25] 7.2
J Wood Capital Advisors LLC Karyopharm Therapeutics Inc [2024-05-23] 5.5
Vanguard Group Inc Karyopharm Therapeutics Inc [2024-02-13] 7.6
Rubric Capital Management LP Karyopharm Therapeutics Inc [2023-02-10] 7.33
BlackRock Inc Karyopharm Therapeutics Inc [2023-01-20] 10.5
Avidity Partners Management LP Karyopharm Therapeutics Inc [2022-12-08] 0.9
Commodore Capital LP Karyopharm Therapeutics Inc [2022-05-09] 5.1
BlackRock Inc Karyopharm Therapeutics Inc [2022-01-27] 11.8
State Street Corp Karyopharm Therapeutics Inc [2021-02-11] 7.26
BlackRock Inc Karyopharm Therapeutics Inc [2020-12-08] 10.1
Avoro Capital Advisors LLC Karyopharm Therapeutics Inc [2020-02-14] 0.4
State Street Corp Karyopharm Therapeutics Inc [2020-02-13] 5.14
Adage Capital Partners GP LLC Karyopharm Therapeutics Inc [2019-11-18] 6.37
Integrated Core Strategies US LLC Karyopharm Therapeutics Inc [2019-07-23] 4.7
Point72 Asset Management LP Karyopharm Therapeutics Inc [2019-02-27] 5.6
Consonance Capital Management LP Karyopharm Therapeutics Inc [2019-02-14] 7.73
BlackRock Inc Karyopharm Therapeutics Inc [2018-02-01] 5.6
Ridgeback Capital Investments LP Karyopharm Therapeutics Inc [2018-01-26] 5.5
Point72 Asset Management LP Karyopharm Therapeutics Inc [2017-11-06] 7.3
Wellington Management Group LLP Karyopharm Therapeutics Inc [2016-10-11] 11.83
Palo Alto Investors LLC Karyopharm Therapeutics Inc [2016-02-16] 8.71
BlackRock Inc Karyopharm Therapeutics Inc [2015-02-02] 6.0
Franklin Resources Inc Karyopharm Therapeutics Inc [2014-06-10] 11.9
Chione Ltd Karyopharm Therapeutics Inc [2014-02-18] 34.5
PLIO Ltd Karyopharm Therapeutics Inc [2014-02-18] 10.7
Kauffman Michael Karyopharm Therapeutics Inc [2014-02-14] 5.43
FMR LLC Karyopharm Therapeutics Inc [2014-02-14] 0.0
Delphi Ventures VIII LP Karyopharm Therapeutics Inc [2013-11-15] 7.2
Foresite Capital Fund I LP Karyopharm Therapeutics Inc [2013-11-15] 5.6
Form 3/4/5 Filer 2011 - 2026
Karyopharm Therapeutics Inc
Su Zhen
Pakianathan Deepika
Greene Barry E
Schor Chen
Bohlin Garen G
Oliger Christy J
Poulton Stuart
Mano Michael
Paulson Richard A
Abate Kristin
Cheng Sohanya Roshan
Rangwala Reshma
Macomber Lori
Mirza Mansoor Raza
Mason Michael
Honig Peter
Mitchener Stephen
Shacham Sharon
Frenkel Ran
Kauffman Michael
Shah Jatin
Dolsten Mikael
Demaree John
Lewis Tanya
Primiano Christopher Brett
Garland J Scott
Hadjimichael George
Hadjimichael Andreas
Chione Ltd
Czernik Marcin
Smolokowski Wiaczeslaw
Varadan Anand
Peters Cameron
Thiel Carsten
Falvey Michael
WEG Kenneth E
Todisco Michael
Renz Justin A
Hadjimichael Amalia
Plio Ltd
Jankilevitsch Gregory
Brannelly Paul
Insider Transaction (Form 3/4/5) Date Action Shares Price Value ($)
Mano Michael
Common Stock
2026-03-02 Sell 3,526 $9.41 33,180
Rangwala Reshma
Common Stock
2026-03-02 Sell 5,066 $9.41 47,671
Paulson Richard A
Common Stock
2026-03-02 Sell 12,361 $9.41 116,317
Abate Kristin
Common Stock
2026-03-02 Sell 559 $9.41 5,260
Poulton Stuart
Common Stock
2026-03-02 Sell 5,101 $9.41 48,000
Cheng Sohanya Roshan
Common Stock
2026-03-02 Sell 4,604 $9.41 43,324
Poulton Stuart
Common Stock
2026-02-17 Sell 378 $8.63 3,262
Paulson Richard A
Common Stock
2026-02-05 Grant 81,060 $0.00
Macomber Lori
Common Stock
2026-02-03 Sell 1,626 $6.30 10,244
Macomber Lori
Common Stock
2026-01-31 Grant 32,415 $0.00
Cheng Sohanya Roshan
Common Stock
2026-01-31 Grant 32,415 $0.00
Mano Michael
Common Stock
2026-01-31 Grant 32,415 $0.00
Poulton Stuart
Common Stock
2026-01-31 Grant 32,415 $0.00
Rangwala Reshma
Common Stock
2026-01-31 Grant 32,415 $0.00
Abate Kristin
Common Stock
2026-01-28 Sell 50 $7.03 352
Abate Kristin
Common Stock
2026-01-27 Grant 92 $0.00
Abate Kristin
Common Stock
2026-01-21 Sell 265 $5.96 1,579
Abate Kristin
Common Stock
2025-10-15 Grant 12,799 $0.00
Macomber Lori
Common Stock
2025-10-15 Grant 43,650 $0.00
Cheng Sohanya Roshan
Common Stock
2025-10-15 Grant 43,650 $0.00
showing 20 of 200 most recent transactions
13F Ownership Over TimeHoldersShares Held
2026-03-31 84 24,278,896
2025-12-31 70 8,835,963
2025-09-30 55 2,785,937
2025-06-30 53 3,887,107
2025-03-31 51 3,763,325
2024-12-31 88 61,992,798
2024-09-30 93 61,606,333
2024-06-30 118 69,901,960
2024-03-31 117 77,864,067
2023-12-31 124 76,707,908
2023-09-30 121 78,610,158
2023-06-30 140 79,281,633
Form 13F Holdings
Firm Period DFND Voting Shares
Y-Intercept Hong Kong Ltd [2026-06-30] SOLE 10,375 10,375
Activest Wealth Management [2026-06-30] SOLE 0 66
West Branch Capital LLC [2026-06-30] SOLE 0 3
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