Commodore Capital LP

ITEM 5 – FEES AND COMPENSATION

The fees applicable to each of the Funds are set forth in detail in the corresponding Offering Documents. A
brief summary of such fees is provided below.

Management Fee

Commodore charges the Funds a management fee based on the value of the Funds’ assets under
management (the “Management Fee”). The Management Fee ranges from 1.5% to 1.75% (per annum) of
the net assets of the Funds and is charged monthly in advance on the first business day of each calendar
month. The Management Fee is prorated for any period that is less than a full month.

Commodore has the authority to waive, reduce or calculate differently the Management Fee with respect to
any Investor in its sole discretion, including Investors that are partners, affiliates or employees of
Commodore or the General Partner, members of the immediate family of such persons and trusts or other
entities established by them or for their benefit and certain other persons in the discretion of Commodore.

For Special Investments, the Management Fee is charged on the lower of value or cost of such Special
Investment.

Incentive Allocation

Commodore and/or the General Partner may be paid performance-based compensation, which is
compensation that is based on a share of capital gains on or capital appreciation of the assets of the Funds.

The General Partner is entitled to a performance allocation from the Funds that ranges from 17.5% to 20%
of the net profits (including net unrealized gains) allocated to an Investor over a three- to five-year period
(the “Incentive Allocation Period”), subject to a loss carryforward provision. Depending on the
circumstances, the performance allocation with respect to Special Investments is calculated either at the
time of realization or at the end of the next Incentive Allocation Period.

The General Partner has the authority to waive, reduce or calculate differently the amount of performance
allocation with respect to any Investor in its sole discretion, including Investors that are partners, affiliates
or employees of Commodore or the General Partner, members of the immediate family of such persons and
trusts or other entities established by them or for their benefit and certain other persons in the discretion of
Commodore.

Expenses

In addition to paying Management Fees and performance-based compensation (if applicable), the Funds
will be subject to other expenses in accordance with their respective governing documents. Such expenses
include, without limitation: organizational expenses, including legal expenses and fees of any placement
agent or other broker; expenses related to compliance with applicable law or regulation, including expenses
related to U.S. and non-U.S. regulatory filings, compliance with the Alternative Investment Fund Managers
Directive 2011/61/EU, “blue sky” and “world sky” filings and anti-money laundering laws and regulations;
investment-related expenses (whether or not such investments are consummated), including commissions,
interest expenses and other indebtedness, investment-related legal costs, custodial fees, brokerage and
transaction costs, research and investment-related travel expenses, professional fees for consultants, “expert
networks,” “sourcing” consultants and other similar persons, data and research-related expenses (including
news and quotation equipment and services), costs of portfolio exposure and performance reporting, risk
management and trade order management expenses; ongoing operating expenses, including administrative
expenses for regulatory and legal compliance, accounting and tax accounting, communications equipment
and services and other back-office and mid-office services (including administrator fees and expenses),
litigation, investigation and indemnity expenses, audit, tax preparation and related advisory expenses,
insurance costs (including directors’ and officers’ insurance, errors and omissions insurance, cybersecurity
insurance and other similar policies), expenses of preparing and distributing reports to Investors (including
financial statements, tax returns and other reports), taxes, expenses of communications and meetings with
Investors, and extraordinary expenses.

Certain expenses may be attributable to more than one Client. Such shared expenses will, to the extent
permitted by the Clients’ governing documents, generally be apportioned among all participating Clients
pro rata based on, without limitation and depending on the nature of the expense, position size, fund size
(i.e., capital commitments or net asset value, as applicable), available cash, or in any other manner deemed
equitable by Commodore. The Firm seeks to allocate shared expenses for products and services benefitting
Commodore and the Client and not explicitly covered in the Client’s arrangements in a fair and reasonable
manner.

ITEM 7 – TYPES OF CLIENTS

Our current Clients are the Funds, as described in Item 4 above. The Funds are generally open to, among
others, institutions, pension plans, endowments, high net-worth individuals, financially sophisticated
individuals, and other sophisticated investors.

There are minimum investment requirements for investors in the Funds. In all cases, the minimum
investment required for a Fund is subject to waiver by Commodore to the extent permitted by applicable
law. Details can be found in the respective Offering Documents of the Funds.